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ARS Home » Southeast Area » Athens, Georgia » U.S. National Poultry Research Center » Exotic & Emerging Avian Viral Diseases Research » Research » Publications at this Location » Publication #395720
Research Project: Intervention Strategies to Predict, Prevent, and Control Emerging Strains of Virulent Newcastle Disease Viruses

Location: Exotic & Emerging Avian Viral Diseases Research

Title: Genetic diversity of Newcastle disease viruses circulating in wild and synanthropic birds in Ukraine between 2007 and 2015

Author
item GORAICHUCK, IRYNA - National Institute Of Experimental And Clinical Veterinary Medicine
item GERILOVYCH, ANTON - National Institute Of Experimental And Clinical Veterinary Medicine
item BOLOTIN, VITALIY - National Institute Of Experimental And Clinical Veterinary Medicine
item SOLODIANKIN, OLEXII - National Institute Of Experimental And Clinical Veterinary Medicine
item DIMITROV, KIRIL - Consultant
item RULA, OLEKSANDR - National Institute Of Experimental And Clinical Veterinary Medicine
item MUZYKA, NATALIIA - National Institute Of Experimental And Clinical Veterinary Medicine
item MEZINOV, OLEKSANDR - National Agrarian University - Ukraine
item STEGNIY, BORYS - National Institute Of Experimental And Clinical Veterinary Medicine
item KOLESNYK, OLENA - National Institute Of Experimental And Clinical Veterinary Medicine
item Pantin Jackwood, Mary
item MILLER, PATTI - Former ARS Employee
item AFONSO, CLAUDIO - Former ARS Employee
item MUZYKA, DENYS - National Institute Of Experimental And Clinical Veterinary Medicine

Submitted to: Frontiers in Veterinary Science
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 1/2/2023
Publication Date: 1/19/2023
Citation: Goraichuck, I.V., Gerilovych, A., Bolotin, V., Solodiankin, O., Dimitrov, K.M., Rula, O., Muzyka, N., Mezinov, O., Stegniy, B., Kolesnyk, O., Pantin Jackwood, M.J., Miller, P.J., Afonso, C.L., Muzyka, D. 2023. Genetic diversity of Newcastle disease viruses circulating in wild and synanthropic birds in Ukraine between 2007 and 2015. Frontiers in Veterinary Science. 10:1026296. https://doi.org/10.3389/fvets.2023.1026296.
DOI: https://doi.org/10.3389/fvets.2023.1026296

Interpretive Summary: Newcastle disease virus (NDV) is one of the most important avian pathogens worldwide. Virulent variants of the virus cause Newcastle disease, which may be devastating, particularly in unvaccinated poultry flocks. It is important to characterize and classify all naturally circulating strains of NDV and the role of wild birds in the spread of NDV. In this study, the sequences of NDVs collected from wild birds in different regions of Ukraine from 2007 to 2015 were analyzed and compared with viruses from other continents. Several genotypes of NDV were detected, some identical to poultry vaccine strains, and some similar to NDV circulating in Kazakhstan. Additionally, some wild bird sequences demonstrated the possible exchange of NDV strains between wild waterfowl of the Azov-Black Sea region of Ukraine with Asia and Africa.

Technical Abstract: Newcastle disease virus (NDV) infects a wide range of bird species worldwide and is of importance to the poultry industry. Although a wealth of information about this virus has accumulated to date, the role of wild birds in the global circulation of NDV is still unclear. It is not entirely certain which NDV sub-genotypes wild birds are capable of spreading and whether there is a seasonality in the detection of the virus. In this study, we performed a phylogenetic analysis of 9 NDV sequences from wild and synanthropic birds collected from different regions of Ukraine from 2007 to 2015. Also, Ukrainian NDV strains were phylogenetically compared with isolates from other continents. In synanthropic birds, NDV strains of genotype II, VI, and XXI of class II were detected. The Fusion gene sequences of genotype II strains were identical to the LaSota vaccine strains detected in different geographical regions. Additionally, our results indicated a possible connection of Ukrainian NDV isolates with strains of genotype XXI circulating in Kazakhstan. Among strains from wild birds, only NDV’s of genotype I class II were detected. The phylogenetic analysis highlighted the possible exchange of genotype I NDV strains between wild waterfowl of the Azov-Black Sea region of Ukraine with Asia and Africa.