Location: Dale Bumpers Small Farms Research Center
Title: Health risk assessment of volatile organic compounds at daycare facilitiesAuthor
BAYATI, MOHAMED - University Of Missouri | |
VU, DANH - Ho Chi Minh City University Of Technology | |
VO, PHUC - University Of Missouri | |
ROGERS, ELIZABETH - University Of Missouri | |
PARK, JIHYUN - University Of Missouri | |
HO, THI - Cuu Long Delta Rice Research Institute | |
DAVIS, ALEXANDRA - University Of New Mexico | |
GULSEVEN, ZEHRA - University Of California Irvine | |
CARLO, GUSTAVO - University Of California Irvine | |
PALERMO, FRANCISCO - University Of Missouri | |
MCELROY, JANE - University Of Missouri | |
NAGEL, SUSAN - University Of Missouri | |
LIN, CHUN-HO - University Of Missouri |
Submitted to: International Journal of Environmental Research and Public Health
Publication Type: Peer Reviewed Journal Publication Acceptance Date: 1/30/2021 Publication Date: 2/15/2021 Citation: Bayati, M., Vu, D.C., Vo, P.H., Rogers, E., Park, J., Ho, T.L., Davis, A.N., Gulseven, Z., Carlo, G., Palermo, F., Mcelroy, J.A., Nagel, S.C., Lin, C. 2021. Health risk assessment of volatile organic compounds at daycare facilities. International Journal of Environmental Research and Public Health. https://doi.org/10.1111/ina.12801. DOI: https://doi.org/10.1111/ina.12801 Interpretive Summary: Children are particularly vulnerable to many classes of the volatile organic compounds (VOCs) detected in indoor environments. The negative health impacts associated with chronic and acute exposures of the VOCs might lead to health issues such as genetic damage, cancer, and disorder of nervous systems. In this study, 40 VOCs including aldehydes and ketones, aliphatic hydrocarbons, esters, aromatic hydrocarbons, cyclic terpenes, alcohols, and glycol ethers were identified and qualified in different locations at the University of Missouri (MU) Child Development Laboratory (CDL) in Columbia, Missouri. Results suggest that the concentrations of the VOCs varied significantly among classrooms, hallways, and playground. Technical Abstract: Children are particularly vulnerable to many classes of the volatile organic compounds(VOCs) detected in indoor environments. The negative health impacts associated with chronic and acute exposures of the VOCs might lead to health issues such as genetic damage, cancer, and disorder of nervous systems. In this study, 40 VOCs including aldehydes and ketones, aliphatic hydrocarbons, esters, aromatic hydrocarbons, cyclic terpenes, alcohols, and glycol ethers were identified and qualified in different locations at the University of Missouri (MU) Child Development Laboratory (CDL) in Columbia, Missouri. Our results suggested that the concentrations of the VOCs varied significantly among classrooms, hallways, and playground. The VOCs emitted from personal care and cleaning products had the highest indoor levels (2-ethylhexanol-1,3-carene,homomenthyl salicylate with mean concentration of 5.15 µg/m3, 1.57 µg/m3, and 1.47 µg/m3, respectively). A cancer risk assessment was conducted, and none of the 95th percentile dose estimates exceeded the age-specific no significant risk levels (NSRL) in all classrooms. Dimensionless toxicity index scores were calculated for all VOCs using a novel web-based framework called Toxicological Prioritization Index (ToxPi), which integrates multiple sources of toxicity data. According to the method, homomenthyl salicylate, benzothiazole, 2-ethylhexyl salicylate, hexadecane, and tridecane exhibited diverse toxicity profiles and ranked as the five most toxic indoor VOCs. The findings of this study provide critical information for policy makers and early education professionals to mitigate the potentially negative health impacts of indoor VOCs in the childcare facilities. |