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ARS Home » Pacific West Area » Davis, California » Western Human Nutrition Research Center » Obesity and Metabolism Research » Research » Publications at this Location » Publication #393950

Research Project: Improving Public Health by Understanding Metabolic and Bio-Behavioral Effects of Following Recommendations in the Dietary Guidelines for Americans

Location: Obesity and Metabolism Research

Title: Chicken liver and eggshell crackers as a safe and affordable animal source food for overcoming micronutrient deficits during pregnancy and lactation in Indonesia: A double-blind, randomised placebo-controlled trial

Author
item DIANA, ALY - Padjadjaran University
item RAHMANNIA, SOFA - Padjadjaran University
item SUHADI, YENNI - Padjadjaran University
item LUFTIMAS, DIMAS - Padjadjaran University
item RIZQI, HAIDAR - Padjadjaran University
item PURNAMASARI, AFINI - Padjadjaran University
item JIHADILLAH, AYUNDA - Padjadjaran University
item ANSARI, MOHAMMAD - Padjadjaran University
item HAQ, DEARLY - Padjadjaran University
item PRATIWI, AISYAH - Padjadjaran University
item SCOTT, SAMUEL - International Food Policy Researc Institute (IFPRI)
item HAMPEL, DANIELA - University Of California, Davis
item Allen, Lindsay - A
item HASZARD, JILLIAN - University Of Otago
item HOUGHTON, LISA - University Of Otago
item GIBSON, ROSALYND - University Of Otago
item FAHMIDA, UMI - Southeast Asian Ministers Of Education Organization Regional Centre For Food And Nutrition (seamo R

Submitted to: Wellcome Open Research
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 5/11/2022
Publication Date: 6/9/2022
Citation: Diana, A., Rahmannia, S., Suhadi, Y.Z., Luftimas, D.E., Rizqi, H., Purnamasari, A.D., Jihadillah, A., Ansari, M.B., Haq, D.A., Pratiwi, A.N., Scott, S., Hampel, D., Allen, L.H., Haszard, J.J., Houghton, L.A., Gibson, R.S., Fahmida, U. 2022. Chicken liver and eggshell crackers as a safe and affordable animal source food for overcoming micronutrient deficits during pregnancy and lactation in Indonesia: A double-blind, randomised placebo-controlled trial (SISTIK growth study). Wellcome Open Research. 7:167. https://doi.org/10.12688/wellcomeopenres.17879.1.
DOI: https://doi.org/10.12688/wellcomeopenres.17879.1

Interpretive Summary: Reduction in child stunting is the first goal of the WHO Global Nutrition Targets for 2025. Indonesia has the the fifth highest burden of stunted children in the world with large variation of the prevalence of stunting across different regions, showing the need to investigate so that appropriate interventions can be implemented. The overall goal of this trial is assess the effectiveness of daily consumption of locally produced MEC by mothers during pregnancy and for five months post partum on infant birth length and linear growth of breastfed infants to 5 months of age, among other secondary outcomes. Here, we describe the study design and protocols for this double-blind, ramdomized placebo controlled trial.

Technical Abstract: Reduction in child stunting is the first goal of the WHO Global Nutrition Targets for 2025. Indonesia has the the fifth highest burden of stunted children in the world with large variation of the prevalence of stunting across different regions, showing the need to investigate so that appropriate interventions can be implemented.The primary objective is to asses the effectiveness of daily consumption of MEC by mothers at two time intervals: (i) from the 8-14 weeks of pregnancy to delivery (i.e., 28-34 weeks of consumption of MEC) on birth length, and (ii) from the 8-14 weeks of pregnancy to 5 months post-partum on attained linear growth and linear growth velocity of breast-fed infants. Secondary outcomes will include: (a) birth weight; (b) maternal haemoglobin at 35-36 weeks gestation; (c) breastmlk volume and micronutrient concentrations in breastmilk at 5 months post-partum; (d) maternal dietary intakes at 8-14 weeks and 35-36 weeks of pregnancy; and 2 and 5 months post-partum; (e) maternal micronutrient status at 35-36 weeks and 5 months post-partum; (f) micronutrient status of breastfeeding infants at aged 5 months; (g) assesment infant neurodevelopment at 2 and 5 m double-blind, ramdomized placebo controlled trial.