Location: Dale Bumpers Small Farms Research CenterTitle: Effect of copper oxide wire particles with and without anthelmintic treatment or anthelmintic treatment alone on gastrointestinal nematode (GIN) fecal egg counts in goats.
|WHITLEY, NIKI - Fort Valley State University|
|DYKES, GREG - Fort Valley State University|
|VAZQUEZ, J - Fort Valley State University|
|TERRILL, THOMAS - Fort Valley State University|
Submitted to: Journal of Animal Science
Publication Type: Abstract Only
Publication Acceptance Date: 1/1/2021
Publication Date: 5/12/2021
Citation: Whitley, N.C., Dykes, G., Vazquez, J., Burke, J.M., Terrill, T.H. 2021. Effect of copper oxide wire particles with and without anthelmintic treatment or anthelmintic treatment alone on gastrointestinal nematode (GIN) fecal egg counts in goats.. Journal of Animal Science. 99(Suppl.2);43. https://doi.org/10.1093/jas/skab096.079.
Technical Abstract: In two experiments (Exp), naturally parasite-infected 5-8 mo-old intact male Spanish goats were used to determine the effect of copper oxide wire particles (COWP; 1 g bolus Copasure®) and levamisole (12 mg/kg; LEV; Prohibit®) or albendazole (20 mg/kg; ALB, Valbazen ®, Exp 2 only) alone or in combination with COWP. Goats were selectively dewormed based on a FAMACHA© eyelid color scoring of =3 with n=12 and 13 for Exp 1 and 2, respectively for COWP alone, n=14/Exp for LEV; n=12/Exp for COWP and levamisole (LC), and for Exp 2 only, n=10 for COWP and albendazole (AC) and n=12 for ALB. Untreated goats were included (CON; n =11) in Exp. 2. Fecal samples were collected using a gloved finger technique on D 0 and 14 in Exp 1 and D 0 and 10 for Exp 2 for determination of fecal egg counts (FEC) using a modified McMaster’s technique with a 50 egg/g sensitivity and calculation of FEC reduction (RED; ((D 0 FEC-D 14 FEC)/D 0 FEC)*100). Data were analyzed with GLM using SAS. Larval culture (Exp 1) indicated 99.8% Haemonchus contortus on D 0. Mean RED was greater for LC than LEV and COWP (Exp 1; P < 0.04) for Exp 1 (Day 14). For Exp 2, mean RED was greater (P < 0.04) for AC than ALB and CON but not COWP and was greater (P < 0.03) for LC compared CON and COWP but not LEV. In these two studies, COWP resulted in > 93% reduction in FEC and only improved results in combination with LEV in Exp 1 in which the drug alone was less effective than the other treatments (and RED was measured 14 d after treatment).