|Medrano, Enrique - Gino|
|HAYDEL, SHELLEY - Arizona State University|
Submitted to: Microbiology Resource Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 10/23/2021
Publication Date: 11/11/2021
Citation: Medrano, E.G., Haydel, S.E. 2021. Complete genome sequence of the methicillin-resistant Staphylococcus aureus strain SQL1/USA300, used for testing the antimicrobial properties of clay phyllosilicates and customized aluminosilicates. Microbiology Resource Announcements. 10(45). Article e00861-21. https://doi.org/10.1128/MRA.00861-21.
Interpretive Summary: Staphylococcus is a type of bacteria that occurs in all environments and is the primary pathogen responsible for infections in hospitals and other medical care facilities. This bacteria is also transmitted into cotton plants by stink bugs, but the impact of Staphylococcus colonization in cotton plants is not known. We sequenced and assembled the genome of an antibiotic-resistant strain of Staphylococcus aureas, commonly known as MRSA, to identify the gene(s) involved in the infection process which, in turn, can be targeted to control infection. The work also improves our understanding of why some strains of bacteria can cause disease in plants or humans, while other strains of the same bacteria produce no disease symptoms.
Technical Abstract: Methicillin Resistant Staphylococcus aureus (MRSA) is a Gram-positive bacterium with strains that cause community-acquired and nosocomial infections. Recently, we showed the antimicrobial capacity of clay components with potency to deter the virulent MRSA strain SQL1. The annotated genome contributes critical knowledge of MRSA infectivity and potential targets for infection control.