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ARS Home » Southeast Area » Athens, Georgia » U.S. National Poultry Research Center » Exotic & Emerging Avian Viral Diseases Research » Research » Publications at this Location » Publication #380776

Research Project: Intervention Strategies to Predict, Prevent and Control Disease Outbreaks Caused by Emerging Strains of Virulent Newcastle Disease Viruses

Location: Exotic & Emerging Avian Viral Diseases Research

Title: Near-complete genome sequences of five sicinivirus from North America

item GORAICHUK, IRYNA - Orise Fellow
item DAVIS, JAMES - Georgia Poultry Laboratory Network
item PARRIS, DARREN - Orise Fellow
item KARIITHI, HENRY - Orise Fellow
item Afonso, Claudio
item Suarez, David

Submitted to: Microbiology Resource Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 4/15/2021
Publication Date: 5/14/2021
Citation: Goraichuk, I.V., Davis, J.F., Parris, D.J., Kariithi, H.M., Afonso, C.L., Suarez, D.L. 2021. Near-complete genome sequences of five sicinivirus from North America. Microbiology Resource Announcements. 10(19):e00364-21.

Interpretive Summary: Through the use of next generation sequencing methods, we were able to sequence several viruses from clinical samples without the need of growing the viruses in the laboratory. Close to full length sequences of several sicinvirus isolates from the USA and Mexico were identified from chicken samples. Currently it is unclear if siciniviruses cause clinical disease , but the viruses which are in the picornavirus family have at least some association with digestive and growth issues. The identification of the genetic sequence allows for more targeted studies to be performed that can help determine if these viruses are pathogens.

Technical Abstract: Here, we report near-complete genome sequences of sicinivirus from U.S. poultry flocks in 2003 to 2005 and Mexico in 2019. They show highest nucleotide identity (84.5 to 85.5%) with other members of the Sicinivirus genus. These sequences update knowledge on diversity and contribute to a better understanding of the molecular epidemiology of sicinivirus.