Skip to main content
ARS Home » Plains Area » Manhattan, Kansas » Center for Grain and Animal Health Research » Hard Winter Wheat Genetics Research » Research » Publications at this Location » Publication #376831

Research Project: Genetic Improvement of Biotic and Abiotic Stress Tolerance and Nutritional Quality in Hard Winter Wheat

Location: Hard Winter Wheat Genetics Research

Title: A monophyletic Fusarium that includes the Fusarium solani species complex is strongly supported by a 19-gene phylogenomic analysis

item GEISER, DAVID - Pennsylvania State University
item AL-HATMI, ABDULLAH - Ministry Of Health
item AOKI, TAKAYUKI - National Agriculture And Food Research Organization (NARO), Agricultrual Research Center
item ARIE, TSUTOMU - Tokyo University Of Agriculture & Technology
item BALMAS, VIRGILIO - Dipartimento Di Agraria, Universita Degli Studi Di Sassari
item BARNES, IRENE - University Of Pretoria
item BERGSTROM, GARY - Cornell University
item BHATTACHARYYA, MADAN - Iowa State University
item BLOOMQUIST, CHERYL - California Department Of Food And Agriculture
item Bowden, Robert - Bob
item BRANKOVICS, BALAZS - Wageningen University And Research Center
item Brown, Daren
item BURGESS, LESTER - University Of Sydney
item BUSHLEY, KATHRYN - University Of Minnesota
item Busman, Mark
item CANO-LIRA, JOSE - University Rovira I Virgili
item CARILLO, JOSEPH - University Of Florida
item CHANG, HAO-XUN - National Taiwan University
item CHEN, CHI-YU - National Chung-Hsing University
item CHEN, WANQUAN - Chinese Academy Of Agricultural Sciences
item CHILVERS, MARTIN - Michigan State University
item CHULZE, SOFIA - National University Of Rio Cuarto
item COLEMAN, JEFFREY - Auburn University
item CUOMO, CHRISTINA - Broad Institute Of Mit/harvard
item DE BEER, WILHELM - University Of Pretoria
item DE HOOG, SYBREN - Radboud University
item DEL CASTILLO-MUNERA, JOHANNA - University Of California, Davis
item DEL PONTE, EMERSON - Universidade Federal De Vicosa
item DIEGUEZ-URIBEONDO, JAVIER - Real Jardin Bolancio Csic
item DI PIETRO, ANTONIO - Universidad De Cordoba
item EDEL-HERMANN, VERONIQUE - French National Institute For Agricultural Research
item ELMER, WADE - Connecticut Agricultural Experiment Station
item EPSTEIN, LYNN - University Of California, Davis
item ESKALEN, AKIF - University Of California, Davis
item ESPOSTO, MARIA CARMELA - Universita Degli Studi Di Salerno
item EVERTS, KATHRYNE - University Of Maryland
item FERNANDEZ-PAVIA, SYLVIA - Universidad Michoacana De San Nicolas De Hidalgo
item FOROUD, NORA - Lethbridge Research Center
item FOURIE, GERDA - University Of Pretoria
item FRANDSEN, RASMUS J.N. - Technical University Of Denmark
item FREEMAN, STANLEY - Volcani Center (ARO)
item FREITAG, MICHAEL - Oregon State University
item FRENKEL, OMER - Volcani Center (ARO)
item FULLER, KEVIN - University Of Oklahoma Health Sciences Center
item GAGKAEVA, TATIANA - All-Russian Institute For Plant Protection
item GARDINER, DONALD - Csiro European Laboratory
item Glenn, Anthony - Tony
item Gold, Scott
item GORDON, THOMAS - University Of California, Davis
item GRYZENHOUT, MARIEKA - University Of The Free State
item GUARRO, JOSEP - University Rovira I Virgili
item GUGINO, BETH - Pennsylvania State University
item GUTIERREZ, SANTIAGO - University Of Leon
item Kim, Hye-Seon
item Kistler, Harold
item Lofton, Lily
item LARABA, IMANE - Oak Ridge Institute For Science And Education (ORISE)
item Martin, Frank
item McCormick, Susan
item O Donnell, Kerry
item Proctor, Robert
item Rehner, Stephen
item Vaughan, Martha
item Ward, Todd

Submitted to: Phytopathology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 11/13/2020
Publication Date: 9/9/2021
Citation: Geiser, D.M., Al-Hatmi, A., Aoki, T., Arie, T., Balmas, V., Barnes, I., Bergstrom, G.C., Bhattacharyya, M.K., Bloomquist, C.L., Bowden, R.L., Brankovics, B., Brown, D.W., Burgess, L.W., Bushley, K., Busman, M., Cano-Lira, J.F., Carillo, J.D., Chang, H., Chen, C., Chen, W., Chilvers, M., Chulze, S., Coleman, J.J., Cuomo, C.A., De Beer, W., De Hoog, S., Del Castillo-Munera, J., Del Ponte, E.M., Dieguez-Uribeondo, J., Di Pietro, A., Edel-Hermann, V., Elmer, W.H., Epstein, L., Eskalen, A., Esposto, M., Everts, K.L., Fernandez-Pavia, S.P., Ferreira Da Silva, G., Foroud, N.A., Fourie, G., Frandsen, R., Freeman, S., Freitag, M., Frenkel, O., Fuller, K.K., Gagkaeva, T., Gardiner, D.M., Glenn, A.E., Gold, S.E., Gordon, T., Gryzenhout, M., Guarro, J., Gugino, B.K., Gutierrez, S., Kim, H., Kistler, H.C., Lofton, L., Laraba, I., Martin, F.N., Mccormick, S.P., O Donnell, K., Proctor, R., Rehner, S.A., Vaughan, M.M., Ward, T.J. 2021. A monophyletic Fusarium that includes the Fusarium solani species complex is strongly supported by a 19-gene phylogenomic analysis. Phytopathology.

Interpretive Summary: Fusarium is regarded as one of the most economically destructive groups of toxin-producing plant pathogens and emergent human pathogens. The diverse toxins they produce frequently contaminate food and feed, making it unsuitable for consumption by humans and other animals. Thus, they pose a significant global threat to food safety, agricultural biosecurity, and plant, human and animal health. Reduction in yields and quality due to Fusarium-induced diseases are responsible for multibillion-dollar annual losses to the global agricultural economy. Therefore, in our interconnected global economy, it is essential that plant disease specialists and quarantine officials worldwide use the same name for the same pathogen responsible for an outbreak or epidemic. DNA data is the current gold standard for rapidly and accurately identifying Fusarium pathogens throughout the world. In this study, which is coauthored by a nearly unanimous global Fusarium community, DNA sequences of 19 genes from 84 fusaria and closely related species were analyzed genetically to evaluate evolutionary relationships and determine what groups were supported as belonging in Fusarium. The comparative genomics analysis provided strong statistical support for inclusion of several early branching lineages in Fusarium, including the F. solani species complex (FFSC). The FSSC comprises more than 90 species that were recently misclassified in the genus Neocosmospora. There are potentially serious consequences associated with using the name Neocosmospora for Fusarium species because clinicians and plant pathologists need to be aware that fusaria are broadly resistant to the spectrum of antifungals/fungicides that are currently available. To fix this problem, the Neocosmospora species were reclassified here as Fusarium where they belong. The research reported here, which represents the most detailed evolutionary genetic assessment of the genus Fusarium to date, will be of interest to plant pathologists, mycotoxicologists, medical mycologists and quarantine officials worldwide.

Technical Abstract: The Fusarium solani species complex (FSSC) represents a monophyletic group of phylogenetically diagnosable species, including many important plant pathogens. Previously (Geiser et al. 2013 Phytopathology 103:400-408. 2013), the Fusarium community nearly unanimously voiced support for a concept of Fusarium that represented a clade comprising all economically important Fusarium species, including the FSSC. Since then, papers published from the Westerdijk Insititute in the Netherlands (Lombard et al. 2015; Sandoval-Denis and Crous 2018; Sandoval-Denis et al. 2018, 2019) have promoted splitting Fusarium into seven genera, including the FSSC as the genus Neocosmospora. One of these publications (Sandoval-Denis and Crous 2018) claims that the Geiser et al. (2013) concept of Fusarium is polyphyletic, and that their concept of Neocosmospora reflected a "more natural" taxonomic approach. Here we point out that these claims are incontrovertibly false, bolstered with a phylogeny based on 19 orthologous protein-coding genes that demonstrates robust monophyly of Fusarium inclusive of the FSSC. In recognition of this, we recombined 40 species recently described as Neocosmospora into Fusarium, and renamed nine others. We re-assert the practical and scientific argument in support of a Fusarium that includes the FSSC and several other basal lineages, consistent with the longstanding use of this name among plant pathologists, medical mycologists and other citizens, students and researchers with a stake in its taxonomy. The nearly unanimous global Fusarium community will continue to view the FSSC as Fusarium, as it is the best scientific, nomenclatural and practical taxonomic option available.