Skip to main content
ARS Home » Pacific West Area » Albany, California » Western Regional Research Center » Healthy Processed Foods Research » Research » Publications at this Location » Publication #376486

Research Project: Prevention of Obesity Related Metabolic Diseases by Bioactive Components of Food Processing Waste Byproducts and Mitigation of Food Allergies

Location: Healthy Processed Foods Research

Title: Chemistry of pterostilbene and its metabolic effects

item KIM, HYUNSOOK - Hanyang University
item SEO, KUN-HO - Konkuk University
item Yokoyama, Wallace - Wally

Submitted to: Journal of Agricultural and Food Chemistry
Publication Type: Review Article
Publication Acceptance Date: 3/3/2020
Publication Date: 3/3/2020
Citation: Kim, H., Seo, K., Yokoyama, W.H. 2020. Chemistry of pterostilbene and its metabolic effects. Journal of Agricultural and Food Chemistry.

Interpretive Summary: Pterostilbene, a bioactive plant polyphenol, is similar in structure to resveratrol and has many of the same beneficial properties to human health. USDA scientist, Dr. Agnes Rimando, discovered many of the health benefits of pterostilbene and in collaboration with research scientists around the globe established the beneficial properties of pterostilbene. Pterostilbene was found to improve risk factors for diabetes, cardiovascular disease, fatty liver disease, Alzheimer’s disease and others.

Technical Abstract: Pterostilbene, 3',5'-dimethoxy-4-hydroxystilbene, is a resveratrol analogue and has been reported to have similar and often potent health-promoting properties. Pterostilbene has been shown to reduce weight gain, liver fat, plasma cholesterol, adiposity, inflammatory biomarkers, blood glucose, and other physiological characteristics of metabolic diseases in animal models. Studies on pterostilbene suggest that it may improve risk factors associated with diabetes, cardiovascular disease, fatty liver diseases, Alzheimer’s disease, and other neurodegenerative diseases. Many of the extensive studies on the potential health benefits of pterostilbene were conducted by Dr. Agnes Rimando, a scientist with the United States Department of Agriculture, in collaboration with many U.S. and other international research groups. This review highlights the pterostilbene research of Dr. Rimando.