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ARS Home » Midwest Area » Peoria, Illinois » National Center for Agricultural Utilization Research » Renewable Product Technology Research » Research » Publications at this Location » Publication #375216

Title: alpha-Glucan Polysaccharide Combined with Feruloyl Soy Glyceride to form Novel Nanoparticles

Author
item Evans, Kervin
item Compton, David
item Skory, Christopher

Submitted to: Pacific Basin Society Chemical International Congress Abstracts
Publication Type: Abstract Only
Publication Acceptance Date: 12/16/2020
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: An increasing need for nanoparticles with the capability of encapsulating hydrophobic materials has led us to develop water-insoluble alpha-glucans into nanoparticles. The alpha-glucans we used are agri-based biopolymers synthesized using recombinant glucansucrase from Leuconostoc mesenteroides. These glucan nanoparticles made through high-pressure homogenization were shown to have a hydrophobic core and have a stability greater than 7 months. The glucan nanoparticles also have characteristic size and surface potential between 110 – 150 nm and -8 to -3 mV, respectively. We have combined the alpha-glucans in a 1-to-2 weight-to-weight ratio with feruloyl soy glycerides, a modified soybean oil, to form a novel feruloyl soy glyceride-glucan (FSGG) nanoparticle system. Analysis shows that the FSGG nanoparticles are about 239 nm in diameter and have a surface potential of about -15.5 mV. FSGG nanoparticles exhibit a stability of at least two weeks, remaining homogenously mixed in water without precipitation. This is the first demonstration of a novel phytochemically modified soybean oil being encapsulated within a nanoparticles system. These combined agri-based molecule and polymer have great potential as a novel, biodegradable delivery system.