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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Virus and Prion Research » Research » Publications at this Location » Publication #367809
Research Project: Non-Antibiotic Strategies to Control Priority Bacterial Infections in Swine

Location: Virus and Prion Research

Title: Bordetella bronchiseptica and respiratory disease in swine

Author
item HAU, SAMANTHA - Orise Fellow
item Brockmeier, Susan

Submitted to: Review Article
Publication Type: Review Article
Publication Acceptance Date: 9/30/2019
Publication Date: 10/1/2019
Citation: Hau, S.J., Brockmeier, S. 2019. Bordetella bronchiseptica and respiratory disease in swine. Review Article. p.1-21.

Interpretive Summary:

Technical Abstract: B. bronchiseptica is a ubiquitous pathogen of swine causing respiratory infections including rhinitis, tracheitis, bronchitis, and pneumonia. It spreads quickly between animals, especially during commingling of naïve animals with subclinical carriers. B. bronchiseptica causes disease through the production of virulence factors, such as adhesins and toxins, which is coordinated by the BvgAS system. In addition to causing primary disease, B. bronchiseptica can exacerbate viral respiratory infections and predispose animals to other bacterial respiratory pathogens, which increases the clinical significance of B. bronchiseptica colonization. Disease is currently managed with antibiotic treatments and vaccination strategies; however, colonization is difficult to clear and animals can remain colonized and shed B. bronchiseptica long term, acting as a source of infection for naïve animals within a herd.