|KWON, JUNGHOON - Consultant|
|BAHL, JUSTIN - University Of Georgia|
|LEE, YOUN-JEONG - Animal And Plant Quarantine Agency|
|SONG, CHANG-SEON - Konkuk University|
|LEE, DONG-HUN - University Of Connecticut|
Submitted to: Transboundary and Emerging Diseases
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 10/25/2019
Publication Date: 3/6/2020
Citation: Kwon, J., Bahl, J., Swayne, D.E., Lee, Y., Song, C., Lee, D. 2019. Domestic ducks play a major role in maintenance and spread of H5N8 highly pathogenic avian influenza viruses in South Korea. Transboundary and Emerging Diseases. 14:257–265. https://doi.org/10.1111/tbed.13406.
Interpretive Summary: During 2014-2016 H5N8 highly pathogenic avian influenza viruses (HPAIV) induced the longest outbreak in South Korea and caused severe economic loss in poultry. To understand how H5N8 HPAIV spread at host species level in Korea, we estimate transmission pathway between wild waterfowl, domestic ducks, and chickens. Our result indicated that domestic duck population plays a central role in the maintenance, amplification and spread of wild HPAIV to gallinaceous poultry in Korea.
Technical Abstract: The H5N8 highly pathogenic avian influenza viruses (HPAIV) belonging to clade 18.104.22.168 spread from Eastern China to Korea in 2014 and caused outbreaks in domestic poultry until 2016. To understand how H5N8 HPAIV spread at host species level in Korea during 2014-2016, a Bayesian phylogenetic analysis was used for ancestral state reconstruction and estimation of the host transition dynamics between wild waterfowl, domestic ducks, and chickens. Our data supports that H5N8 HPAIV most likely transmitted from wild waterfowl to domestic ducks, then maintained in domestic ducks followed by dispersal of HPAIV from domestic ducks to chickens, suggesting domestic duck population plays a central role in the maintenance, amplification and spread of wild HPAIV to gallinaceous poultry in Korea.