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ARS Home » Plains Area » Clay Center, Nebraska » U.S. Meat Animal Research Center » Meat Safety & Quality Research » Research » Publications at this Location » Publication #356121

Research Project: Genomic and Metagenomic Differences in Foodborne Pathogens and Determination of Ecological Niches and Reservoirs

Location: Meat Safety & Quality Research

Title: Closed genome sequence of Escherichia coli K-12 group strain C600

item ALLUE-GUARDIA, ANNA - University Of Texas At San Antonio
item NYONG, EMMANUEL - University Of Texas At San Antonio
item KOENIG, SARAH - University Of Texas At San Antonio
item VARGAS, SEAN - University Of Texas At San Antonio
item Bono, James - Jim
item EPPINGER, MARK - University Of Texas At San Antonio

Submitted to: Microbiology Resource Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 12/6/2018
Publication Date: 1/10/2019
Citation: Allue-Guardia, A., Nyong, E.C., Koenig, S.S.K., Vargas, S.M., Bono, J.L., Eppinger, M. 2019. Closed genome sequence of Escherichia coli K-12 group strain C600. Microbiology Resource Announcements. 8:e1052-18.

Interpretive Summary: Escherichia coli has been used worldwide for over a half a century to study bacterial physiology, molecular microbiology and microbial genetics. Since its isolation in 1922, E. coli strain K12 was the first strain used in many experiments and has since given rise to many derived strains that have different characteristics. Strain C600 is one of these descendant strains and has the ability to incorporate foreign DNA into its chromosome and is susceptible to infection by bacterial viruses. The genome of strain C600 was sequenced to provide information about the genetic make-up of this isolate. The availability of the closed high-quality genome for strain C600 is foundational to further clarify sites where foreign DNA or bacterial viruses gets incorporated into its chromosome and how this additional genetic information affects the host.

Technical Abstract: Escherichia coli strain C600 is a prototypical K-12 derived laboratory strain which has been broadly used for molecular microbiology and bacterial physiology studies since its isolation in 1954. Here, we present the closed genome sequence of E. coli strain C600, retrieved from the American Type Culture Collection (ATCC 23724).