|Dawson-hughes, Bess - Jean Mayer Human Nutrition Research Center On Aging At Tufts University|
|Bischoff-ferrara, Heike - University Hospital Zurich|
Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: 7/12/2016
Publication Date: 3/1/2018
Citation: Dawson-Hughes, B., Bischoff-Ferrara, H.A. Adult vitamin D deficiency: fracture and fall prevention. 2018. In: Feldman, D., Editor. Vitamin D. 4th edition. Cambridge, MA: Academic Press. p. 221-226. https://doi.org/10.1016/B978-0-12-809963-6.00069-9.
DOI: https://doi.org/10.1016/B978-0-12-809963-6.00069-9 Interpretive Summary:
Technical Abstract: This chapter summarizes the impact of vitamin D deficiency on adult bone and muscle health and discusses whether the effect of vitamin D on fall risk contributes to its benefit on fracture prevention. Fall prevention is essential in fracture prevention at higher age. Evidence from randomized-controlled trials is reviewed for fall and fracture prevention based on recent meta-analyses. These meta-analyses consider the role of the dose of vitamin D administered, the type of dwelling (free living versus nursing home), and treatment interval. Finally, trial and epidemiological data will be reviewed to estimate the serum 25-hydroxyvitamin D (25(OH)D) level needed for optimal bone and muscle health.