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ARS Home » Southeast Area » Stoneville, Mississippi » Crop Production Systems Research » Research » Publications at this Location » Publication #354465

Research Project: Biology and Management of Herbicide-Resistant Weeds

Location: Crop Production Systems Research

Title: Herbicide metabolism: Crop selectivity, bioactivation, weed resistance mechanisms, and regulation

item Nandula, Vijay
item RIECHERS, DEAN - University Of Illinois
item FERHATOGLU, YURDAGUL - University Of Kentucky
item BARRETT, MICHAEL - University Of Kentucky
item Duke, Stephen
item DAYAN, FRANCK - Colorado State University
item GOLDBERG-CAVALLERI, ALINA - Newcastle University
item TETARD-JONES, CATHERINE - Newcastle University
item WORTLEY, DAVID - Boult Wade Tennant
item ONKOKESUGN, NAWAPORN - Newcastle University
item BRAZIER-HICKS, MELISSA - Newcastle University
item EDWARDS, ROBERT - Newcastle University
item GAINES, TODD - Colorado State University
item IWAKAMI, SATOSHI - Kyoto University
item JUGULAM, MITHILA - Kansas State University
item MA, RONG - University Of Idaho

Submitted to: Weed Science
Publication Type: Review Article
Publication Acceptance Date: 11/6/2018
Publication Date: 3/25/2019
Citation: Nandula, V.K., Riechers, D.E., Ferhatoglu, Y., Barrett, M., Duke, S.O., Dayan, F.E., Goldberg-Cavalleri, A., Tetard-Jones, C., Wortley, D.J., Onkokesugn, N., Brazier-Hicks, M., Edwards, R., Gaines, T., Iwakami, S., Jugulam, M., Ma, R. 2019. Herbicide metabolism: Crop selectivity, bioactivation, weed resistance mechanisms, and regulation. Weed Science. 67:149-175.

Interpretive Summary:

Technical Abstract: Several grass and broadleaf weed species around the world have evolved multiple herbicide resistance at alarmingly increasing rates, which is becoming more of a norm than an exception. Research on the biochemical and molecular resistance mechanisms of multiple resistant weed populations indicate a prevelance of herbicide metabolism brought about by enzyme systems such as cytochrome P450 monoxygenases and glutathione-S-transferases, and to a lesser extent, by glucosyl transferases. A symposium was conducted to gain an understanding of the current state of research affairs of metabolic resistance mechanisms in weed species that pose major management problems around the world. These topics as well as future directions of investigations that were identified in the symposium are summarized herein. In addition, the latest information on selected topics such as the role of safeners in crop tolerance to herbicides, selectivity to clomazone, glyphosate metabolism in crops and weeds, and bioactivation of natural molecules is reviewed.