Skip to main content
ARS Home » Northeast Area » Boston, Massachusetts » Jean Mayer Human Nutrition Research Center On Aging » Research » Publications at this Location » Publication #352370

Research Project: Sarcopenia, Nutrition, and Physical Activity

Location: Jean Mayer Human Nutrition Research Center On Aging

Title: Emerging impact of skeletal muscle in health and disease

Author
item Fielding, Roger - Jean Mayer Human Nutrition Research Center On Aging At Tufts University
item Ralston, Stuart - University Of Edinburgh
item Rizzoli, Rene - University Of Geneva

Submitted to: Calcified Tissue International
Publication Type: Other
Publication Acceptance Date: 10/20/2014
Publication Date: 2/17/2015
Citation: Fielding, R.A., Ralston, S.H., Rizzoli, R. 2015. Emerging impact of skeletal muscle in health and disease. Calcified Tissue International. 96(3):181-182. https://doi.org/10.1007/s00223-015-9.
DOI: https://doi.org/10.1007/s00223-015-9

Interpretive Summary:

Technical Abstract: It has been over 60 years since Huxley first described the essential force transmitting properties of voluntary striated skeletal muscle. At no time since then has the importance of skeletal muscle integrity been more pronounced. Although skeletal muscle comprises 40-50% of total body mass, this tissue has been relatively understudied compared to brain, liver, cardiac, bone, and other tissues. Despite the fact that skeletal muscle is necessary for locomotion, oxygen consumption, whole-body energy metabolism, and substrate turnover and storage, a relative lack of attention has been paid to this tissue that is essential for many daily functions and activities.