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ARS Home » Northeast Area » Ithaca, New York » Robert W. Holley Center for Agriculture & Health » Plant, Soil and Nutrition Research » Research » Publications at this Location » Publication #344811

Research Project: Development and Application of Genetic, Genomic, and Bioinformatic Resources in Maize

Location: Plant, Soil and Nutrition Research

Title: Rapid cycling genomic selection in a multiparental tropical maize population

Author
item ZHANG, XUECAI - INTERNATIONAL MAIZE & WHEAT IMPROVEMENT CENTER (CIMMYT)
item PEREZ-RODRIGUEZ, PAULINO - COLEGIO DE POSTGRADUADOS
item BURGUENO, JUAN - INTERNATIONAL MAIZE & WHEAT IMPROVEMENT CENTER (CIMMYT)
item OLSEN, MICHAEL - INTERNATIONAL MAIZE & WHEAT IMPROVEMENT CENTER (CIMMYT)
item Buckler, Edward - Ed
item ATLIN, GARY - GATES FOUNDATION
item PRASANNA, BODDUPALLI - INTERNATIONAL MAIZE & WHEAT IMPROVEMENT CENTER (CIMMYT)
item VARGAS, MATEO - UNIVERSITY OF CHAPINGO
item SAN VINCENTE, FELIX - INTERNATIONAL MAIZE & WHEAT IMPROVEMENT CENTER (CIMMYT)
item CROSSA, JOSE - INTERNATIONAL MAIZE & WHEAT IMPROVEMENT CENTER (CIMMYT)

Submitted to: Genes, Genomes, and Genomics
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 5/15/2017
Publication Date: 7/1/2017
Citation: Zhang, X., Perez-Rodriguez, P., Burgueno, J., Olsen, M., Buckler IV, E.S., Atlin, G., Prasanna, B., Vargas, M., San Vincente, F., Crossa, J. 2017. Rapid cycling genomic selection in a multiparental tropical maize population. Genes, Genomes, and Genomics. 7(7):2315-2326.

Interpretive Summary: Plant breeding rests on combining and mixing genetic diversity as efficiently and rapidly as possible. Genomic selection relies on using DNA profiles across an entire genome to rapidly identify the best varieties to advance to the next generation using all available information on how its relatives grew in the past. In this study, genomic selection was applied to rapidly advance a multi-parent breeding approach, and it was shown to have substantial success. Yield was increased consistently by 2.5% per cycle even for this diverse tropical germplasm. This shows the tremendous potential for increasing yield of tropical germplasm if genomic selection can be regularly applied and used across the developing world.

Technical Abstract: Genomic selection (GS) increases genetic gain by reducing the length of the selection cycle, as has been exemplified in maize using rapid cycling recombination of biparental populations. However, no results of GS applied to maize multi-parental populations have been reported so far. This study is the first to show realized genetic gains of rapid cycling genomic selection (RCGS) for four recombination cycles in a multi-parental tropical maize population. Eighteen elite tropical maize lines were intercrossed twice, and self-pollinated once, to form the cycle 0 (C0) training population. A total of 1000 ear-to-row C0 families was genotyped with 955,690 genotyping-by-sequencing SNP markers; their testcrosses were phenotyped at four optimal locations in Mexico to form the training population. Individuals from families with the best plant types, maturity, and grain yield were selected and intermated to form RCGS cycle 1 (C1). Predictions of the genotyped individuals forming cycle C1 were made, and the best predicted grain yielders were selected as parents of C2; this was repeated for more cycles (C2, C3, and C4), thereby achieving two cycles per year. Multi-environment trials of individuals from populations C0, C1, C2, C3, and C4, together with four benchmark checks were evaluated at two locations in Mexico. Results indicated that realized grain yield from C1 to C4 reached 0.225 ton ha-1 per cycle, which is equivalent to 0.100 ton ha-1 yr-1 over a 4.5-yr breeding period from the initial cross to the last cycle. Compared with the original 18 parents used to form cycle 0 (C0), genetic diversity narrowed only slightly during the last GS cycles (C3 and C4). Results indicate that, in tropical maize multi-parental breeding populations, RCGS can be an effective breeding strategy for simultaneously conserving genetic diversity and achieving high genetic gains in a short period of time.