Submitted to: Journal of AOAC International
Publication Type: Review Article
Publication Acceptance Date: 9/5/2017
Publication Date: 5/1/2018
Citation: Busman, M. 2018. Quantitation of mycotoxins using direct analysis in real time mass spectrometry (DART-MS). Journal of AOAC International. 101(3):643-646. https://doi.org/10.5740/jaoacint.17-0338.
Technical Abstract: Ambient ionization represents a new generation of mass spectrometry ion sources which is used for rapid ionization of small molecules under ambient conditions. The combination of ambient ionization and mass spectrometry allows analyzing multiple food samples with simple or no sample treatment, or in conjunction with prevailing sample preparation methods. Two ambient ionization methods, desorptive electrospray ionization (DESI) and direct analysis in real time (DART) have been adapted to food safety applications. Both ionization techniques provide unique advantages and capabilities. DART has been utilized for a variety of qualitative and quantitative applications. In particular, mycotoxin contamination of food and feed materials has been addressed by DART-MS. Applications to mycotoxin analysis by ambient ionization mass spectrometry, and particularly DART-MS are summarized.