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ARS Home » Plains Area » Fargo, North Dakota » Edward T. Schafer Agricultural Research Center » Animal Metabolism-Agricultural Chemicals Research » Research » Publications at this Location » Publication #343434

Research Project: Environmental Chemical Residues and Their Impact in the Food Supply

Location: Animal Metabolism-Agricultural Chemicals Research

Title: Fate and transport of three antibiotics in laboratory batch partitioning studies using beef lagoon runoff water

item WOODWARD, KATHERINE - Tufts University
item Hakk, Heldur
item Lupton, Sara
item Woodbury, Bryan
item GUTE, DAVID - Tufts University

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 5/14/2017
Publication Date: 10/16/2017
Citation: Woodward, K., Hakk, H., Lupton, S.J., Woodbury, B.L., Gute, D. 2017. Fate and transport of three antibiotics in laboratory batch partitioning studies using beef lagoon runoff water [abstract]. 33 Annual International Conference on Soils, Sediments, Water, and Energy. October 16-19, 2017. Amherst, MA. p. 262.

Interpretive Summary:

Technical Abstract: Antimicrobial overuse and resistance (AMR) are of growing concern to the scientific community. Antimicrobials are used prophylactically and therapeutically during production of meat animals to maintain herd health and as such, many of these antimicrobial residues end up in runoff water. When runoff water is used as irrigation for crop production, these residues become available for transport in the environment. Therefore, cost-effective methods need to be developed for removing antimicrobial residues from the wastewater. The objective of this study was to identify how select antimicrobial residues are partitioned in runoff wastewater to provide information on how to design more effective control systems. Therefore, three radiolabeled antibiotics, 14C-erythromycin (ERY), 3H-chlortetracycline (CTC), and 3H-monensin (MON) were selected for a laboratory batch partitioning study utilizing beef lagoon runoff. Liquid scintillation counting and oxidation were used to quantify the radioactivity in the aqueous and sorbed fractions. Slightly more ERY partitioned to the sorbed fraction than the aqueous fraction, and equilibrium conditions existed from 2 to 168 h. CTC partitioning occurred in two phases: a rapid sorption to the particle fraction between 0.5 and 8 h with desorption beginning at 24 h into the aqueous fraction, this suggested degradation/metabolism to more polar compounds. The most lipophilic antibiotic, MON, quickly and nearly quantitatively partitioned into the sorbed fraction, and remained at equilibrium with the aqueous fraction from 0.5 to 168 h. This information will be used to develop treatment designs and methods for antibiotic removal in lagoon wastewater.