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ARS Home » Northeast Area » Wyndmoor, Pennsylvania » Eastern Regional Research Center » Molecular Characterization of Foodborne Pathogens Research » Research » Publications at this Location » Publication #342829

Research Project: Advanced Development of Innovative Technologies and Systematic Approaches to Foodborne Hazard Detection and Characterization for Improving Food Safety

Location: Molecular Characterization of Foodborne Pathogens Research

Title: Electrical chips for biological point-of-care detection

item Reddy, Bobby - Purdue University
item Salm, Eric - Purdue University
item Bashir, Rashid - Purdue University

Submitted to: Annals of Biomedical Engineering
Publication Type: Review Article
Publication Acceptance Date: 4/2/2016
Publication Date: 7/1/2016
Citation: Reddy, B., Salm, E., Bashir, R. 2016. Electrical chips for biological point-of-care detection. Annals of Biomedical Engineering. 18:329-355.

Interpretive Summary:

Technical Abstract: As the future of health care diagnostics moves toward more portable and personalized techniques, there is immense potential to harness the power of electrical signals for biological sensing and diagnostic applications at the point of care. Electrical biochips can be used to both manipulate and sense biological entities, as they can have several inherent advantages, including on-chip sample preparation, label-free detection, reduced cost and complexity, decreased sample volumes, increased portability, and large-scale multiplexing. The advantages of fully integrated electrical biochip platforms are particularly attractive for point-of-care systems, including on-site detection of harmful bacteria. This review summarizes these electrical lab-on-a-chip technologies and highlights opportunities to accelerate the transition from academic publications to commercial success.