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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Infectious Bacterial Diseases Research » Research » Publications at this Location » Publication #342609

Research Project: Characterize the Immunopathogenesis and Develop Diagnostic and Mitigation Strategies to Control Tuberculosis in Cattle and Wildlife

Location: Infectious Bacterial Diseases Research

Title: Genome sequences of Escherichia coli strains that cause persistent and transient mastitis

Author
item Thacker, Tyler
item Lippolis, John
item Brunelle, Brian
item Casey, Thomas
item Reinhardt, Timothy - Tim
item Sacco, Randy
item Holman, Devin - U.s. Department Of Agriculture (USDA)

Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 7/3/2017
Publication Date: 8/24/2017
Citation: Thacker, T.C., Lippolis, J.D., Brunelle, B.W., Casey, T., Reinhardt, T.A., Sacco, R.E., Holman, D.B. 2017. Genome sequences of Escherichia coli strains that cause persistent and transient mastitis. Genome Announcements. 5(34):e00775-17. https://doi.org/10.1128/genomeA.00775-17.
DOI: https://doi.org/10.1128/genomeA.00775-17

Interpretive Summary: DNA from two strains of the bacteria Escherichia coli that cause mastitis in dairy cattle were sequenced. One strain is known to cause a short infection while the other causes a persistent infection. Sequencing these bacteria is the first step in understanding there molecular mechanisms that cause these different type of infections.

Technical Abstract: The genomes of two strains of Escherichia coli that cause bovine mastitis were sequenced. These strains are known to be associated with persistent and transient mastitis: strain ECA-B causes a transient infection, and ECC-M leads to a persistent infection.