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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Infectious Bacterial Diseases Research » Research » Publications at this Location » Publication #342609
Research Project: Characterize the Immunopathogenesis and Develop Diagnostic and Mitigation Strategies to Control Tuberculosis in Cattle and Wildlife

Location: Infectious Bacterial Diseases Research

Title: Genome sequences of Escherichia coli strains that cause persistent and transient mastitis

Author
item Thacker, Tyler
item Lippolis, John
item Brunelle, Brian
item Casey, Thomas
item Reinhardt, Timothy
item Sacco, Randy
item HOLMAN, DEVIN - US Department Of Agriculture (USDA)

Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 7/3/2017
Publication Date: 8/24/2017
Citation: Thacker, T.C., Lippolis, J.D., Brunelle, B.W., Casey, T., Reinhardt, T.A., Sacco, R.E., Holman, D.B. 2017. Genome sequences of Escherichia coli strains that cause persistent and transient mastitis. Genome Announcements. 5(34):e00775-17. https://doi.org/10.1128/genomeA.00775-17.
DOI: https://doi.org/10.1128/genomeA.00775-17

Interpretive Summary: DNA from two strains of the bacteria Escherichia coli that cause mastitis in dairy cattle were sequenced. One strain is known to cause a short infection while the other causes a persistent infection. Sequencing these bacteria is the first step in understanding there molecular mechanisms that cause these different type of infections.

Technical Abstract: The genomes of two strains of Escherichia coli that cause bovine mastitis were sequenced. These strains are known to be associated with persistent and transient mastitis: strain ECA-B causes a transient infection, and ECC-M leads to a persistent infection.