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ARS Home » Southeast Area » Athens, Georgia » U.S. National Poultry Research Center » Poultry Microbiological Safety and Processing Research Unit » Research » Publications at this Location » Publication #338546
Research Project: Production and Processing Intervention Strategies for Poultry Associated Foodborne Pathogens

Location: Poultry Microbiological Safety and Processing Research Unit

Title: Evaluation of encapsulated sodium butyrate on growth performance, energy digestibility, gut development and Salmonella effect in broilers

Author
item LIU, JUNDI - University Of Georgia
item BAYIR, H - University Of Georgia
item Cosby, Douglas
item Cox Jr, Nelson
item WILLIAMS, SUSAN - University Of Georgia
item FOWLER, JUSTIN - University Of Georgia

Submitted to: Poultry Science
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 5/1/2017
Publication Date: 7/28/2017
Citation: Liu, J.D., Bayir, H.O., Cosby, D.E., Cox Jr, N.A., Williams, S.M., Fowler, J. 2017. Evaluation of encapsulated sodium butyrate on growth performance, energy digestibility, gut development and Salmonella effect in broilers. Poultry Science. 96(10):3638-3644. doi.org/10.3382/ps/pex174.
DOI: https://doi.org/10.3382/ps/pex174

Interpretive Summary: Experiments were conducted to determine the effect of encapsulated sodium butyrate on broiler performance, energy digestibility, intestinal morphology and colonization of the ceca by Salmonella Typhimurium. Sodium butyrate had an effect on effect of body weight and intestinal morphology resulting in a positive influence on the intestinal absorptive surface area but did not prevent or suppress cecal colonization of Salmonella Typhimurium.

Technical Abstract: Two experiments were conducted to determine the effect of an encapsulated sodium butyrate (Na-B) with different releasing times on broiler performance, energy digestibility, intestinal morphology and Salmonella colonization. In experiment 1, three different Na-B (CMA, CMP and CMS) were evaluated following a challenge with a nalidixic acid resistant Salmonella Typhimurium (STNAR). A total of 384 Cobb-Cobb male birds were placed 8 birds per pen into 6 replicates for each treatment. Treatments included six Na-B treatments (500 and 1000 ppm of each product) plus two control (non-challenged and challenged control). Birds were orally gavaged with 0.1 mL of 107 cfu/mL STNAR on d 4. Ceca and ileal samples were collected on d 11. In experiment 2, CMA and CMP products were evaluated for a full growth-out period without an extra challenge. The 1080 Cobb-Cobb male birds were distributed among 45 floor pens with 24 birds per pen. Treatments included four product treatments (500 and 1000 ppm of each product) plus one control. Feed intake and pen weight were obtained on d 14, 28 and 42. Experiment 1 showed that CMP at 1000 ppm had the highest value for BW and BWG on d 4 (P = 0.07). Adding CMA and CMP at 500 ppm had the highest (P = 0.05) ileal digestibility energy (IDE). The Salmonella recovery data indicated that the challenge had a significant, but mild impact since it did not affect the performance variables but did result in a significant increase in log CFU between challenged and unchallenged treatments (3.72 vs 1.42). Experiment 2 showed that both products treatments significantly improved the ileal morphology on d 21 and IDE on d 42 than the control (P = 0.05). This study demonstrates that Na-B has the potential to improve growth for broilers at an early age within an experimental challenge condition. The beneficial effects on intestinal morphology and IDE are affected not only by dosage level, but also by the product’s releasing time.