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ARS Home » Pacific West Area » Logan, Utah » Poisonous Plant Research » Research » Publications at this Location » Publication #338424

Research Project: Understanding and Mitigating the Adverse Effects of Poisonous Plants on Livestock Production Systems

Location: Poisonous Plant Research

Title: Toxic causes of intestinal disease in horses

Author
item Stegelmeier, Bryan
item Davis, Thomas - Zane

Submitted to: Veterinary Clinics of North America
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 8/1/2017
Publication Date: 2/5/2018
Citation: Stegelmeier, B.L., Davis, T.Z. 2018. Toxic causes of intestinal disease in horses. Veterinary Clinics of North America. 34(1):127-139. https://doi.org/10.1016/j.cveq.2017.11.008.
DOI: https://doi.org/10.1016/j.cveq.2017.11.008

Interpretive Summary: As most poisonings occur by toxin ingestion, the gastrointestinal system is first exposed and in most cases it is exposed to the highest toxin concentrations. Consequently stomach and intestine damage is common. However, as many toxins produce organ specific damage, and gastrointestinal damage is easily confused with post mortem change and many gastrointestinal lesions are overlooked or overshadowed by other clinical and pathologic changes. The objectives of this work is to review several common toxins and poisonous plants that produce primarily gastrointestinal disease.

Technical Abstract: As most poisonings occur by toxin ingestion, the gastrointestinal system is first exposed and in most cases it is exposed to the highest toxin concentrations. Consequently enterocyte damage is common. However, as many toxins produce organ specific damage, and enterocyte necrosis is easily confused with autolysis, many gastrointestinal lesions are overlooked or overshadowed by other clinic and pathological changes. The objectives of this work is to review several common toxins and poisonous plants that produce primarily gastrointestinal disease.