Submitted to: Citrograph
Publication Type: Trade Journal
Publication Acceptance Date: 12/15/2016
Publication Date: 2/6/2017
Citation: Lin, H., Duan, Y., Shi, X. 2017. Develop a novel target-basis of anti-virulence strategy for controlling HLB. Citrograph. p. 60-62.
Technical Abstract: The goal of this CRB-funded research project is to develop target-based anti-virulence therapeutics for Huanglongbing (HLB). Since the first report of citrus HLB in Florida in 2005, the disease is now looming large in Texas and California. In Florida, citrus growers are encountering severe decline of trees and premature fruit drop. HLB is a devastating disease: All citrus cultivars that are grown commercially are susceptible to HLB and an effective psyllid vector control is not available. Thus, an immediate and effective method to mitigate HLB and prevent new infection is urgently needed. In this progress report, research strategy is briefly described as well as the overall experimental approach. Finally, research is reported on progress on the identification and assessment of anti-virulence compounds to suppress and mitigate the effects of HLB.