|PETERSON, JULIA - Tufts University|
|DWYER, JOHANNA - National Institutes Of Health (NIH)|
|JACQUES, PAUL - Jean Mayer Human Nutrition Research Center On Aging At Tufts University|
|MCCULLOUGH, MARJORIE - American Cancer Society|
Submitted to: Nutrition Reviews
Publication Type: Review Article
Publication Acceptance Date: 10/21/2014
Publication Date: 6/16/2015
Citation: Peterson, J.J., Dwyer, J.T., Jacques, P.F., Mccullough, M.L. 2015. Improving the estimation of flavonoid intake for study of health outcomes. Nutrition Reviews. 73(8):553-576. doi: 10.1093/nutrit/nuv008.
Technical Abstract: Imprecision in estimating intakes of non-nutrient bioactive compounds such as flavonoids is a challenge in epidemiologic studies of health outcomes. The sources of this imprecision, using flavonoids as an example, include the variability of bioactive compounds in foods due to differences in growing conditions and processing, the challenges in laboratory quantification of flavonoids in foods, the incompleteness of flavonoid food composition tables, and the lack of adequate dietary assessment instruments. Steps to improve databases of bioactive compounds and to increase the accuracy and precision of the estimation of bioactive compound intakes in studies of health benefits and outcomes are suggested.