Location: Plant Gene Expression CenterTitle: Plant Immunity
Submitted to: Seminars in Cell and Developmental Biology
Publication Type: Other
Publication Acceptance Date: 5/24/2016
Publication Date: 7/4/2016
Citation: Lewis, J.D. 2016. Plant Immunity. Seminars in Cell and Developmental Biology. 56C, p.121.
Interpretive Summary: Many different pathogens, including bacteria, fungi, viruses and nematodes cause substantial crop losses. Although plants lack an antibody-based adaptive immune system, they can defend themselves using a variety of different strategies. Understanding the molecular, genetic and cellular events associated with resistance can inform strategies to prevent plant disease and protect crops.
Technical Abstract: Plants are faced with defending themselves against a multitude of pathogens, including bacteria, fungi, viruses, nematodes, etc. Immunity is multi-layered and complex. Plants can induce defenses when they recognize small peptides, proteins or double-stranded RNA associated with pathogens. Recognition of pathogens also causes transcriptional changes, hormone signaling, cellular events and protein trafficking. Understanding the molecular events underpinning immunity has aided in the development of cultivars that are resistant to pathogens.