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Research Project: Pediatric Clinical Nutrition

Location: Children's Nutrition Research Center

Title: Depressive symptoms in youth with type 1 or type 2 diabetes: Results of the Pediatric Diabetes Consortium screening assessment of depression in diabetes study

Author
item Silverstein, Janet - University Of Florida
item Cheng, Peiyao - Jaeb Center For Health Research
item Ruedy, Katrina - Jaeb Center For Health Research
item Kollman, Craig - Jaeb Center For Health Research
item Beck, Roy - Jaeb Center For Health Research
item Klingensmith, Georgeanna - University Of Colorado
item Wood, Jamie - Children'S Hospital Los Angeles
item Willi, Steven - University Of Pennsylvania
item Bacha, Fida - Children'S Nutrition Research Center (CNRC)
item Lee, Joyce - University Of Michigan
item Cengiz, Eda - Yale University
item Redondo, Maria - Texas Children'S Hospital
item Tamborlane, William - Yale University

Submitted to: Diabetes Care
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 9/9/2015
Publication Date: 12/1/2015
Citation: Silverstein, J., Cheng, P., Ruedy, K.J., Kollman, C., Beck, R.W., Klingensmith, G.J., Wood, J.R., Willi, S., Bacha, F., Lee, J., Cengiz, E., Redondo, M.J., Tamborlane, W.V. 2015. Depressive symptoms in youth with type 1 or type 2 diabetes: Results of the Pediatric Diabetes Consortium screening assessment of depression in diabetes study. Diabetes Care. 38(12):2341-2343.

Interpretive Summary: Depression symptoms are common in children with chronic illness. The prevalence of depression symptoms in youth with diabetes and whether there are differences in these symptoms in children with type 1 vs. type 2 diabetes is unclear. We evaluated depression symptoms in 10-17 year old children with type 1 and type 2 diabetes enrolled in the Pediatric Diabetes Consortium (PDC) US Registry. Symptoms of depression were present in 13% of participants with type 1 diabetes and 22% of those with type 2 diabetes. However, only about half of these children were seen by a therapist in the prior 12 months. Depressive symptoms were associated with lower family income and obesity in the children with type 1 but not type 2 diabetes. Depressive symptoms are more frequent than diagnosed depression in youth with T1D or T2D. These results indicate the need for depression screening and appropriate referral for youth with diabetes.

Technical Abstract: To evaluate the frequency of depressive symptoms and the diagnosis and management of depression in youth with type 1 diabetes (T1D) and type 2 diabetes (T2D) enrolled in the Pediatric Diabetes Consortium T1D and T2D registries. The Children's Depression Inventory (CDI) 2 Self-Report (Short) version was completed by 261 T1D and 339 T2D youth aged 10-17 years. Symptoms of depression were identified in 13% of T1D and 22% of T2D (P = 0.007) participants; of these, only 4% of T1D and 9% of T2D youth were treated by a therapist within the prior 12 months. Depressive symptoms were associated with lower family income (P = 0.006) and obesity (P = 0.002) in T1D but not T2D youth. Depressive symptoms are more frequent than diagnosed depression in youth with T1D or T2D. These results underscore the need for regular depression screening and appropriate referral for youth with diabetes.