|Stroka, J - European Commission-Joint Research Centre (JRC)|
Submitted to: World Mycotoxin Journal
Publication Type: Review Article
Publication Acceptance Date: 6/16/2016
Publication Date: 11/10/2016
Citation: Stroka, J., Maragos, C.M. 2016. Challenges in the analysis of multiple mycotoxins. World Mycotoxin Journal. 9(5):847-861.
Technical Abstract: The problems associated with different groups or “families” of mycotoxins have been known for some time, and for many years certain groups of mycotoxins have been known to co-occur in commodities and foods. Until fairly recently commodities and foods were analyzed for individual toxins or groups of related toxins and attempts to measure multiple groups of toxins required significant investments in terms of time, effort, and expense. Analytical technologies using both the instrument-intensive techniques such as mass spectrometry and screening techniques such as immunoassays have progressed significantly in recent years. This has led to the proliferation of techniques capable of detecting multiple groups of mycotoxins using a variety of approaches. Despite considerable progress, the challenges for routine monitoring of multiple toxins continue. Certain of these challenges, such as the need for co-extraction of multiple analytes with widely different polarities, and the potential for carry-over of matrix components that can influence the results, are independent of the analytical technique (MS or immunoassay) used. Because of the wide variety of analytical platforms used for multi-toxin analysis, there are also specific challenges that arise amongst the analytical platforms. In this article we seek to describe some of the challenges associated with multi-toxin analysis and articulate how such challenges have recently been addressed.