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ARS Home » Midwest Area » Peoria, Illinois » National Center for Agricultural Utilization Research » Mycotoxin Prevention and Applied Microbiology Research » Research » Publications at this Location » Publication #323069

Title: Applications of nanoporous cyclodextrin polymers to prevent exposure to mycotoxins

item Appell, Michael

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 3/17/2016
Publication Date: 3/17/2016
Citation: Appell, M.D. 2016. Applications of nanoporous cyclodextrin polymers to prevent exposure to mycotoxins [abstract].

Interpretive Summary:

Technical Abstract: As a continued effort to maintain a safe food supply, new strategies and technologies are developed in order to reduce human and animal exposure to contaminants. Agricultural commodities are occasionally contaminated by certain species of fungi that produce mycotoxins at levels that are health risks. We have developed and characterized a series of nanoporous beta-cyclodextrin-polyurethane polymers capable of improving the analysis of toxin levels and also the removal of toxins from contaminated beverages. Atomic force microscopy analysis indicated the polymers exhibit irregular surface morphologies. Analytical methods were developed to detect the toxin patulin in apple juice using the cyclodextrin polyurethane polymers as sorbents in solid phase extraction columns. In addition, suitable cyclodextrin polyurethane materials removed ochratoxins from wine (1-10 ng/L). Sorption assays indicated the affinities of the mycotoxins patulin, citrinin, ochratoxin A, and zearalenone were influenced by the cross-linking agents and suggest the binding properties of the cyclodextrin polyurethane polymers could be tuned for applications.