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Research Project: Developmental Determinants of Obesity in Infants and Children

Location: Children's Nutrition Research Center

Title: Ghrelin

item MULLER, TD - Institute For Animal Health
item NOGUEIRAS, R - University Of Santiago De Compostela
item ANDERMANN, ML - Beth Israel Deaconess Medical Center
item ANDREWS, ZB - Monash University
item ANKER, SD - Charite' University Hospital Berlin
item ARGENTE, J - Hospital Infantil
item BATTERHAM, RL - University College London
item BENOIT, SC - University Of Cincinnati
item BOWERS, CY - Tulane University
item BROGLIO, F - University Of Torino
item CASANUEVA, FF - University Of Santiago De Compostela
item D'ALESSIO, D - Duke University
item DEPOORTERE, I - University Of Leuven
item GELIEBTER, A - Columbia University - New York
item GHIGO, E - Columbia University - New York
item COLE, PA - Monash University
item COWLEY, M - Monash University
item CUMMINGS, DE - University Of Washington Medical School
item DAGHER, A - McGill University - Canada
item DIANO, S - Yale University
item DICKSON, SL - Sahlgrenska Academy
item DIEGUEZ, C - University Of Santiago De Compostela
item GRANATA, R - University Of Torino
item GRILL, HJ - University Of Pennsylvania
item GROVE, K - Oregon Health & Science University
item HABEGGER, KM - University Of Alabama
item HEPPNER, K - Oregon Health & Science University
item HOLSEN, L - Harvard Medical School
item HOLST, B - University Of Copenhagen
item INUI, A - Kagoshima University
item JANSSON, JO - Sahlgrenska University Hospital
item KORBONITS, M - Queen Mary University Of London
item LAFERRERE, B - Columbia University - New York
item LEROUX, CW - University College Dublin
item LOPEZ, M - University Of Santiago De Compostela
item MORIN, S - Helmholtz Centre
item NAKAZATO, M - University Of Miyazaki
item NASS, R - University Of Virginia
item PEREZ-TILVE, D - University Of Cincinnati
item PFUGER, PT - Helmholtz Centre
item SCHWARTZ, TW - University Of Copenhagen
item SEELEY, RJ - University Of Michigan
item SLEEMAN, M - Monash University
item SUN, YUXIANG - Children'S Nutrition Research Center (CNRC)
item SUSSEL, L - Columbia University - New York
item TONG, J - Duke University
item THORNER, MO - University Of Virginia
item VAN DER LELY, AJ - Erasmus University
item ZIGMAN, JM - University Of Texas Southwestern Medical Center
item KOJIMA, M - Kurume University
item KANGAWA, K - Baylor College Of Medicine
item SMITH, RG - Scripps Institute
item HORVATH, T - Yale University
item TSCHOP, MH - Helmholtz Centre

Submitted to: Molecular Metabolism
Publication Type: Review Article
Publication Acceptance Date: 3/11/2015
Publication Date: 3/21/2015
Citation: Muller, T., Nogueiras, R., Andermann, M., Andrews, Z., Anker, S., Argente, J., Batterham, R., Benoit, S., Bowers, C., Broglio, F., Casanueva, F., D'Alessio, D., Depoortere, I., Geliebter, A., Ghigo, E., Cole, P., Cowley, M., Cummings, D., Dagher, A., Diano, S., Dickson, S., Dieguez, C., Granata, R., Grill, H., Grove, K., Habegger, K., Heppner, K., Holsen, L., Holst, B., Inui, A., Jansson, J., Korbonits, M., Laferrere, B., Leroux, C., Lopez, M., Morin, S., Nakazato, M., Nass, R., Perez-Tilve, D., Pfuger, P., Schwartz, T., Seeley, R., Sleeman, M., Sun, Y., Sussel, L., Tong, J., Thorner, M., Van Der Lely, A., Van Der Ploeg, L., Zigman, J., Kojima, M., Kangawa, K., Smith, R., Horvath, T., Tschop, M. 2015. Ghrelin. Molecular Metabolism. 4(6):437-460.

Interpretive Summary:

Technical Abstract: The gut hormone ghrelin was discovered in 1999. In the last 15 years, ample data have been generated on ghrelin. Bedsides its hallmark function as an appetite stimulator, ghrelin also has many other important functions. In this review, we discussed ghrelin's functions in learning and memory, gut movement and food digestion, sleep/wake rhythm, reward seeking behavior, taste sensation and glucose regulation. It is anticipated that this comprehensive review will serve as millstone summary for ghrelin research, and inspire future discoveries.