|RILEY, ROBERT - US Department Of Energy|
|HARIDAS, SAJEET - US Department Of Energy|
|SALAMOV, ASAF - US Department Of Energy|
|BOUNDY-MILLS, KYRIA - University Of California|
|GOKER, MARKUS - Leibniz Institute|
|HITTINGER, CHRIS - University Of Wisconsin|
|KLENK, HANS-PETER - Newcastle University|
|LOPES, MARIANA - Newcastle University|
|MEIER-KOLTHOFF, JAN - Newcastle University|
Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 3/22/2015
Publication Date: 3/22/2015
Citation: Riley, R., Haridas, S., Salamov, A., Boundy-Mills, K., Goker, M., Hittinger, C., Klenk, H., Lopes, M., Meier-Kolthoff, J.P., Kurtzman, C.P. 2015. Genomic evolution of the ascomycetous yeasts [abstract].
Technical Abstract: Yeasts are important for industrial and biotechnological processes and show remarkable metabolic and phylogenetic diversity despite morphological similarities. We have sequenced the genomes of 16 ascomycete yeasts of taxonomic and industrial importance including members of Saccharomycotina and Taphrinomycotina. Phylogenetic analysis of these and previously published yeast genomes helped resolve the placement of species including Saitoella complicata, Babjeviella inositovora, Hyphopichia burtonii, and Metschnikowia bicuspidata. Moreover, we find that alternative nuclear codon usage, where CUG encodes serine instead of leucine, are monophyletic within the Saccharomycotina. Most of the yeasts have compact genomes with a large fraction of single exon genes, and a tendency towards more introns in early-diverging species. Analysis of enzyme phylogeny gives insights into the evolution of metabolic capabilities such as xylose fermentation, methanol utilization, and assimilation of alternative carbon sources.