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United States Department of Agriculture

Agricultural Research Service

Research Project: INTEGRATED APPROACHES FOR PROTECTION OF ANIMALS FROM VECTOR-BORNE PATHOGENS

Location: Arthropod-borne Animal Diseases Research

Title: Studying Culicoides vectors of BTV in the post-genomic era: resources, bottlenecks to progress and future directions

Author
item Nayduch, Dana
item Cohnstaedt, Lee
item Saski, Christopher
item Lawson, Daniel
item Kersey, Paul
item Fife, Mark
item Carpenter, Simon

Submitted to: Virus Research
Publication Type: Review Article
Publication Acceptance Date: 12/9/2013
Publication Date: 3/28/2014
Citation: Nayduch, D., Cohnstaedt, L.W., Saski, C., Lawson, D., Kersey, P., Fife, M., Carpenter, S. 2014. Studying Culicoides vectors of BTV in the post-genomic era: resources, bottlenecks to progress and future directions. Virus Research. 182(100):43-49. DOI.org/10.1016/j.virusres.2013.12.009.

Interpretive Summary:

Technical Abstract: Culicoides biting midges (Diptera: Ceratopogonidae) are a major vector group responsible for the biological transmission of a wide variety of globally significant arboviruses, including bluetongue virus (BTV). In this review we examine current biological resources for the study of this genus, with an emphasis on detailing the history of extant colonies and cell lines derived from C. sonorensis, the major vector of BTV in the USA. We then discuss the rapidly developing area of genomic and transcriptomic analyses of biological processes in vectors and introduce the newly formed Culicoides Genomics and Transcriptomics Alliance. Preliminary results from these fields are detailed and finally likely areas of future research are discussed from an entomological perspective describing limitations in our understanding of Culicoides biology that may impede progress in these areas.

Last Modified: 10/20/2017
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