Location: Produce Safety and Microbiology ResearchTitle: Complete genome sequence of the clinical Campylobacter coli isolate 15-537360) Author
|Miller, William - Bill|
|Van vliet, Arnoud|
Submitted to: Genome Announcements
Publication Type: Peer reviewed journal
Publication Acceptance Date: 11/15/2013
Publication Date: 12/12/2013
Citation: Pearson, B.M., Rokney, A., Crossman, L.C., Miller, W.G., Wain, J., Van Vliet, A.H. 2013. Complete genome sequence of the clinical Campylobacter coli isolate 15-537360. Genome Announcements. 1(6):e01056-13. Interpretive Summary: Campylobacter coli, along with the related campylobacter Campylobacter jejuni, cause a large number of cases of human bacterial gastroenteritis. Although the chromosomal DNA sequences of several C. coli and C. jejuni strains have been determined, all of the C. coli chromosomal DNA sequences determined to date have been from agricultural isolates. The chromosomal sequence of C. coli strain 15-537360 is thus the first from a human clinical isolate and will greatly assist in the understanding of the role C. coli plays in human disease. Comparisons of the 15-537360 sequence and those already determined indicate a high level of similarity between the gene content of the various strains, although some differences were noted.
Technical Abstract: Campylobacter coli strain 15-537360 was originally isolated from a 42 year-old patient with gastroenteritis. Here we report its complete genome sequence, which comprises a 1.7 Mbp chromosome and a 29 kbp conjugative cryptic plasmid. This is the first complete genome sequence of a clinical isolate of C. coli.