Submitted to: Vegetos: An International Journal of Plant Research
Publication Type: Proceedings
Publication Acceptance Date: 1/18/2014
Publication Date: 5/27/2014
Citation: Kahlon, T.S. 2014. Physical, Chemical, Bibological, and Biotechnological sciences are incomplete without each other. Proceedings of Society for Plant Science. 26:103-112.
Interpretive Summary: Chemical analysis and chromatographic techniques could not separate plasma lipoproteins; these heart disease causing lipid molecules were separated by equilibrium density gradient ultracentrifugation. Chemical analysis on its own was not sufficient to catch adulteration in olive oil. A combination of molecular biology and bioinformatics technology was used for rapid detection of adulteration up to 5% in olive oil. Similarly, combining physics, chemistry and engineering, the cyclotron was invented, which resulted in advancing nuclear physics, particle physics, molecular and materials science, and nuclear medicine. Coupling photomultiplier tubes with NaI scintillation crystal, revolutionized nuclear imaging and established itself as a core medical imaging modality. These are some of the examples that have moved science forward and demonstrate that physical, chemical, biological, and biotechnological sciences are incomplete without each other.
Technical Abstract: By coupling of mechanics, optics, and mathematics, Theodor Svedberg invented the ultracentrifuge, which allowed separation of important biological materials by high centrifugal force, resulting in physical chemical separation and characterization of atherogenic low density lipoproteins and other biological molecules. Combining physics, chemistry and engineering, Ernest Lawrence invented the cyclotron, resulting in advancing nuclear physics, particle physics, molecular and materials science, and nuclear medicine. Using isotope– C-14, Melvin Calvin elucidated the photosynthesis cycle. Coupling photomultiplier tubes (PMTs) with NaI scintillation crystal, Hal Anger revolutionized nuclear imaging. Shashi Kumar and co-workers used biology and polymerase chain technology for the detection of mislabeled food materials. Combinations of biotechnology, chromatography, analytical chemistry and electron microscopy have resulted in organic chemists’ improved ability to synthesize isoprene compounds of interest. These are some of the examples that have moved science forward and demonstrate that physical, chemical, biological, and biotechnological sciences are incomplete without each other.