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ARS Home » Midwest Area » Peoria, Illinois » National Center for Agricultural Utilization Research » Renewable Product Technology Research » Research » Publications at this Location » Publication #292006

Title: Antioxidant efficacy of feruloyl glycerols in model membranes

item Compton, David - Dave
item Evans, Kervin
item Laszlo, Joseph

Submitted to: American Chemical Society Abstracts
Publication Type: Abstract Only
Publication Acceptance Date: 9/12/2013
Publication Date: 9/12/2013
Citation: Compton, D.L., Evans, K.O., Laszlo, J.A. 2013. Antioxidant efficacy of feruloyl glycerols in model membranes [abstract]. American Chemical Society. Abstract AGFD137.

Interpretive Summary:

Technical Abstract: Ferulic acid and its esters are known to be effective antioxidants. Ethyl ferulate was biocatalytically transesterified with triacylglycerols and long chain alcohols to form a series of lipid-based feruloyl esters: feruloylglycerol, diferuloylglycerol, feruloyldiacylglycerol, diferuloylacylglycerol, and octadecyl ferulate. The feruloylglycerol acted as a rapid antioxidant (50% reduction of DPPH radical < 5 min) in ethanol solutions and diferuloyl glycerol was an intermediate antioxidant (50% reduction of DPPH radical in 5–30 min). Partitioning behavior, bilayer depth, and antioxidant characteristics of the feruloylglycerols were determined in phospholipid vesicles. Each feruloyl glycerol derivative incorporated well into liposomes, proving to be non-destructive to the bilayer. Bilayer depth analysis placed ferulic acid, the feruloylglyceols, and octadecyl ferulate at nearly the same bilayer depth. The feruloylglycerols proved better antioxidants in the liposomes than octadecyl ferulate.