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ARS Home » Plains Area » Clay Center, Nebraska » U.S. Meat Animal Research Center » Genetics, Breeding, and Animal Health Research » Research » Publications at this Location » Publication #291899

Research Project: Genetic and Biological Determinants Of Respiratory Diseases Of Ruminants

Location: Genetics, Breeding, and Animal Health Research

Title: Complete closed genome sequences of Mannheimia haemolytica serotypes A1 and A6 isolated from cattle

Author
item Harhay, Gregory
item Koren, Sergey - Battelle Memorial Institute
item Phillippy, Adam - Battelle Memorial Institute
item Mcvey, D Scott - Scott
item Kuszak, Jennifer - University Of Nebraska
item Clawson, Michael - Mike
item Harhay, Dayna
item Heaton, Michael - Mike
item Chitko Mckown, Carol
item Smith, Timothy - Tim

Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 4/4/2013
Publication Date: 5/16/2013
Citation: Harhay, G.P., Koren, S., Phillippy, A.M., McVey, D.S., Kuszak, J., Clawson, M.L., Harhay, D.M., Heaton, M.P., Chitko-McKown, C.G., Smith, T.P.L. 2013. Complete closed genome sequences of Mannheimia haemolytica serotypes A1 and A6 isolated from cattle. Genome Announcements. 1(3):e00188-13. DOI: 10.1128/GENOMEA.00188-13.

Interpretive Summary: Advanced DNA sequencing and computer algorithms were used to reveal, for the first time, the entire unbroken genetic code of the economically important livestock pathogen Mannhemimia haemolytica.

Technical Abstract: Mannhemimia haemolytica is a respiratory pathogen affecting cattle and related ruminants worldwide. M. haemolytica is commonly associated with Bovine Respiratory Disease Complex (BRDC), a polymicrobial, multifactorial disease. We present the first two complete closed genomes of this species using an automated assembly pipeline requiring no manual finishing.