|ELLIOTT, DIANE - Us Geological Survey (USGS)|
|Wiens, Gregory - Greg|
|HAMMELL, K. LARRY - Atlantic Veterinary College|
|RHODES, LINDA - National Oceanic & Atmospheric Administration (NOAA)|
Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: 8/28/2013
Publication Date: 3/7/2014
Citation: Elliott, D.G., Wiens, G.D., Hammell, K., Rhodes, L.D. 2014. Vaccination against salmonid bacterial kidney disease. In: Gudding, R., Lillehaug, A., Evensen, O., editors. Fish Vaccination. 1st edition. Hoboken, NJ: Wiley & Sons, Ltd. p. 255-272.
Technical Abstract: Bacterial kidney disease (BKD) of salmonid fishes, caused by Renibacterium salmoninarum, has presented challenges for development of effective vaccines, despite several decades of research. The only vaccine against BKD that is commercially licensed is an injectable preparation containing live cells of Arthrobacter davidanieli (proposed nomenclature), a nonpathogenic environmental bacterium with a relatively close phylogenetic relationship to R. salmoninarum. The stimulatory effect of the live vaccine is believed to be associated with an Arthrobacter surface carbohydrate that is similar to the exopolysaccaride of R. salmoninarum. Significant protection of Atlantic salmon (Salmo salar) against BKD, but limited or no protection of Chinook salmon (Oncorhynchus tshawytscha) against the disease, has been observed following intraperitoneal injection of the vaccine. Further research is needed for development of more efficacious BKD vaccines for a wider range of salmonid species.