Location: Healthy Body Weight ResearchTitle: Adipose dysfunction, interaction of reactive oxygen species, and inflammation Author
Submitted to: Advances in Nutrition
Publication Type: Proceedings
Publication Acceptance Date: 8/16/2012
Publication Date: 9/14/2012
Citation: Picklo, M.J., Claycombe, K.J., Meydani, M. 2012. Adipose dysfunction, interaction of reactive oxygen species, and inflammation. Advances in Nutrition. 3:734-735. Interpretive Summary:
Technical Abstract: This American Society for Nutrition sponsored symposium summary contains information about the symposium focus and the general content of speaker presentation. The focus of the symposium was to delineate the significance of obesity-associated reactive oxygen species (ROS), inflammation, and adipose tissue dysfunction. As recent studies indicated that oxidant stress is elevated overall in the body as a result of obesity and adipose dysfunction in obesity involves interactions between inflammatory pathways and reactive oxygen signaling. Currently, there is an incomplete understanding of the relationships of the cell types comprising adipose, their interplay in obesity, and the role oxidant stress that influences these relationships. Thus, by speaker presentations, the audience gained a greater understanding of the interactions that inflammatory stimuli and ROS have upon adipose tissue function and dysfunction.