Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: 10/12/2010
Publication Date: 8/10/2011
Citation: Denlinger, D.L., Yocum, G.D., Rinehart, J.P. 2011. Hormonal Control of Diapause. In: Gilbert, L.I. (Ed.), Insect Endocrinology, Elsevier, Amsterdam. Chapter 10. pp. 430-463. Interpretive Summary:
Technical Abstract: A critical feature of the insect life cycle is the ability to shut down development and enter a period of diapause during inimical seasons. This chapter briefly discusses features of the seasonal environment that program this developmental arrest and examines endocrine processes that preside over this decision. Although many links in the pathway leading from reception of environmental signals to expression of the diapause phenotype remain poorly known, recent advances have defined new elements. Ecdysteroids, juvenile hormones, and the neuropeptides that regulate their synthesis and release are well-known contributors to diapause regulation, but new roles for insulin signaling and newly discovered roles for additional neuropeptides have expanded our understanding of the regulatory schemes controlling diapause. Numerous physiological attributes are common to diapauses in different species and developmental stages, yet the diapause phenotype appears to have evolved numerous times using divergent molecular mechanisms.