Submitted to: Natural Product Communications
Publication Type: Peer reviewed journal
Publication Acceptance Date: 3/7/2010
Publication Date: 5/5/2010
Citation: Wang, W., Ali, Z., Li, X., Khan, I.A. 2010. A New ent-Labdane Diterpene Glycoside form the Leaves of Casearia sylvestris. Natural Product Communications. 5(5):771-774. Interpretive Summary: Casearia sylvestris (Flacourtiaceae) is a shrb or small tree widely distributed in tropical countries of South and Central America. The leaves of C. sylvestris were uesd in Brazil as appetite suppresant and weight loss products. In continuation of our program to search for new chemical and bio-marker of the dietary supplement, the present paper described the seperation and elucidation of a new ent-labdane glycoside sylvestin.
Technical Abstract: Sylvestin (1), a new ent-labdane glycoside, was isolated from the leaves of Casearia sylvestris. The structure was determined on the basis of 1D and 2 D NMR and HR-ESI-MS analyses. The diterpenoid of ent-labdane type was isolated for the first time from C. sylvestris.