Submitted to: Veterinary Clinics of North America
Publication Type: Book / chapter
Publication Acceptance Date: 5/11/2010
Publication Date: 7/1/2010
Citation: Ridpath, J.F. 2010. The Contribution of Infections with Bovine Viral Diarrhea Viruses to Bovine Respiratory Disease. Veterinary Clinics of North America. 26(2):335-348. Interpretive Summary:
Technical Abstract: The contribution of bovine viral diarrhea viruses (BVDV) to the development of bovine respiratory disease is the sum of a number of different factors. These factors include the contribution of acute uncomplicated BVDV infections, the high incidence of respiratory disease in animals persistently infected with BVDV, the immunosuppression that accompanies acute BVDV infections and predisposes animals to secondary infections, and the synergy resulting in increased virulence occurring in co-infections of BVDV with other pathogens. Immunosuppression, which is associated with infection will all BVDV, may have the greatest impact of these factors. Control of BVDV infections rests on reducing exposure by removing BVDV persistently infected animals, increasing herd resistance by vaccination, and instituting bio-control methods that limit the opportunity for introduction of BVDV into herds and management units.