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United States Department of Agriculture

Agricultural Research Service

Title: Ursane Triterpenoids from the Bark of Terminalia arjuna

item Wang, Wei
item Ali, Zulfiqar
item Shen, Yunheng
item Li, Xing-cong
item Khan, Ikhlas

Submitted to: Fitoterapia
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 1/5/2010
Publication Date: 1/15/2010
Citation: Wang, W., Ali, Z., Shen, Y., Li, X., Khan, I.A. 2010. Ursane Triterpenoids from the Bark of Terminalia arjuna. Fitoterapia. 81:480-484.

Interpretive Summary: The bark of T. arjuna is a famous Indian folk medicinal plant used as a cardio-tonic in heart failure, ischaemic cardiomyopathy, atherosclerosis and myocardium necrosis. In continuation to search for new chemical and bio-markers from the medicinal plant T. arjuna used for dietary supplements, five usane triterpenoids including one new ursane triterpene glycosyl ester, 2á,3â-dihydroxyurs-12,18-dien-28-oic acid 28-O-â-D-glucopyranosyl ester were isolated. Herein we report the isolation and structure elucidation of the new metablite. Its structure was identified on the basis of extensive NMR experiments.

Technical Abstract: Five ursane type triterpene glucosyl esters including a new one, 2a,3ß-dihydroxyurs-12,18-dien-28-oic acid 28-O-ß-D-glucopyranosyl ester (1) were isolated from the bark of Terminalia arjuna, along with two known phenolic compounds. It is the first report of ursane type of triterpenoids from this spicies.

Last Modified: 06/25/2017
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