Submitted to: Fitoterapia
Publication Type: Peer reviewed journal
Publication Acceptance Date: 1/5/2010
Publication Date: 1/15/2010
Citation: Wang, W., Ali, Z., Shen, Y., Li, X., Khan, I.A. 2010. Ursane Triterpenoids from the Bark of Terminalia arjuna. Fitoterapia. 81:480-484. Interpretive Summary: The bark of T. arjuna is a famous Indian folk medicinal plant used as a cardio-tonic in heart failure, ischaemic cardiomyopathy, atherosclerosis and myocardium necrosis. In continuation to search for new chemical and bio-markers from the medicinal plant T. arjuna used for dietary supplements, five usane triterpenoids including one new ursane triterpene glycosyl ester, 2á,3â-dihydroxyurs-12,18-dien-28-oic acid 28-O-â-D-glucopyranosyl ester were isolated. Herein we report the isolation and structure elucidation of the new metablite. Its structure was identified on the basis of extensive NMR experiments.
Technical Abstract: Five ursane type triterpene glucosyl esters including a new one, 2a,3ß-dihydroxyurs-12,18-dien-28-oic acid 28-O-ß-D-glucopyranosyl ester (1) were isolated from the bark of Terminalia arjuna, along with two known phenolic compounds. It is the first report of ursane type of triterpenoids from this spicies.