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United States Department of Agriculture

Agricultural Research Service

Title: Levels of humoral antibodies induced by different inactivated vaccines correlate with egg production in commercial layers challenged with virulent Newcastle disease virus)

Author
item Miller, Patti
item Susta, Leonardo
item Brown, Corrie
item Decanini, Eduardo
item Absalon, Angel
item Afonso, Claudio

Submitted to: American Association of Avian Pathologists
Publication Type: Abstract Only
Publication Acceptance Date: 12/30/2009
Publication Date: 8/4/2010
Citation: Miller, P.J., Susta, L., Brown, C.C., Decanini, E.L., Absalon, A.E., Afonso, C.L. 2010. Levels of humoral antibodies induced by different inactivated vaccines correlate with egg production in commercial layers challenged with virulent Newcastle disease virus [abstract]. In: Proceedings of the American Association of Avian Pathologists Annual Meeting, July 31-August 04, 2010, Atlanta, Georgia. paper #9300.

Interpretive Summary:

Technical Abstract: To evaluate the relationship between humoral antibodies from homologous and heterologous vaccines and egg production, twenty-two week-old commercial layers previously vaccinated with four live B1 vaccines were boosted with two different inactivated Newcastle disease virus (NDV) vaccines, a virulent strain, CA02, or a strain of low-virulence, LaSota, and compared to a control group. Three weeks later, serum was collect for hemagglutination-inhibition (HI) assays and the birds were challenged with the CA02 strain, via eye drop and nasal instillation. Serum for HI assay was taken before termination. The sham-boosted birds had a significant decrease in egg production in comparison to birds that were not challenged, or to birds that were boosted with the two different NDV vaccines. A slight decrease in egg production was observed in the LaSota-boosted birds (heterologous) in comparison to the CA02 boosted (homologous), or the non challenged animals.

Last Modified: 8/24/2016
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