Submitted to: Genbank
Publication Type: Other
Publication Acceptance Date: 10/21/2009
Publication Date: 10/21/2009
Citation: Yeh, H., Klesius, P.H. 2009. Tetraspanin 3 and tetraspanin 7 transcripts of channel catfish, Ictalurus punctatus Rafinesque, 1818. Genbank. accession Nos. GU120083 - GU120084. Interpretive Summary:
Technical Abstract: Tetraspanin 3 and tetraspanin 7 proteins are members of the tetraspanin integral membrane protein family. These proteins play many important roles in immuno-physiological functions. In this communication, we sequenced and characterized the channel catfish tetraspanin 3 and tetraspanin 7 transcripts. The full-length nucleotide sequences of channel catfish tetraspanin 3 and tetraspanin 7 cDNA comprised of 1,474 and 1,863 nucleotides, respectively. Each included an open reading frame, which appears to encode a putative peptide of 241 and 251 amino acid residues for tetraspanin 3 and tetraspanin 7, respectively. By comparison with human counterparts, the channel catfish tetraspanin 3 and tetraspanin 7 peptides can be divided into domains, including four transmembrane domains, three intracellular domains, and one of each small and large extracellular loops. The transcripts were detected by RT-PCR in various channel catfish tissues. This result provides important information for further elucidating these tetraspanin proteins in channel catfish.