Skip to main content
ARS Home » Southeast Area » Oxford, Mississippi » Natural Products Utilization Research » Research » Publications at this Location » Publication #246078
Title: Clerodane and Ent-kaurane Diterpene Glycosyl and Glycoside Derivatives from the Leaves of Casearia sylvestris

Author
item WANG, WEI - University Of Mississippi
item ALI, ZULFIQAR - University Of Mississippi
item LI, XING-CONG - University Of Mississippi
item KHAN, IKHLAS - University Of Mississippi

Submitted to: Helvetica Chimica Acta
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 8/19/2009
Publication Date: 8/31/2009
Citation: Wang, W., Ali, Z., Li, X., Khan, I.A. 2009. Clerodane and Ent-kaurane Diterpene Glycosyl and Glycoside Derivatives from the Leaves of Casearia sylvestris. Helvetica Chimica Acta. 92:1829-1839.

Interpretive Summary: Casearia sylvestris Swartz (Flacourtiaceae) is a Brazilian and Paraguayan folk medicinal plant called as “Guaçatonga” or “Chá de Bugre” and used to treat snakebite, trauma, ulceration, obesity, and cough. Our continued investigation of this species has led to identification of five new clerodane diterpene glycosides, caseariasides A-E (1-5) and three ent-kaurane diterpene glucosides, sylvestrisides C-E (6-8). Here, we report the isolation and structure elucidation of these eight new glycosides.

Technical Abstract: Five new clerodane diterpene glycosides caseariasides A-E (1-4) and three new ent-kaurane diterpene glucosides sylvestrisides C-E (6-8) were isolated from the leaves of Casearia sylvestris. Their structures were determined on the basis of chemical and spectroscopic analyses.