Page Banner

United States Department of Agriculture

Agricultural Research Service

Title: Clerodane and Ent-kaurane Diterpene Glycosyl and Glycoside Derivatives from the Leaves of Casearia sylvestris)

Author
item Wang, Wei
item Ali, Zulfiqar
item Li, Xing-cong
item Khan, Ikhlas

Submitted to: Helvetica Chimica Acta
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 8/19/2009
Publication Date: 8/31/2009
Citation: Wang, W., Ali, Z., Li, X., Khan, I.A. 2009. Clerodane and Ent-kaurane Diterpene Glycosyl and Glycoside Derivatives from the Leaves of Casearia sylvestris. Helvetica Chimica Acta. 92:1829-1839.

Interpretive Summary: Casearia sylvestris Swartz (Flacourtiaceae) is a Brazilian and Paraguayan folk medicinal plant called as “Guaçatonga” or “Chá de Bugre” and used to treat snakebite, trauma, ulceration, obesity, and cough. Our continued investigation of this species has led to identification of five new clerodane diterpene glycosides, caseariasides A-E (1-5) and three ent-kaurane diterpene glucosides, sylvestrisides C-E (6-8). Here, we report the isolation and structure elucidation of these eight new glycosides.

Technical Abstract: Five new clerodane diterpene glycosides caseariasides A-E (1-4) and three new ent-kaurane diterpene glucosides sylvestrisides C-E (6-8) were isolated from the leaves of Casearia sylvestris. Their structures were determined on the basis of chemical and spectroscopic analyses.

Last Modified: 8/24/2016
Footer Content Back to Top of Page