Submitted to: United States-Japan Cooperative Program in Natural Resources
Publication Type: Abstract Only
Publication Acceptance Date: 7/15/2008
Publication Date: 8/24/2008
Citation: Holser, R.A., Himmelsbach, D.S. 2008. Correlation spectroscopy applied to glycerol polyester spectra. United States-Japan Cooperative Program in Natural Resources, Food, and Agriculture; August 24-28, 2008, Chicago, IL. Interpretive Summary:
Technical Abstract: The recent development of glycerol polyesters for use as controlled release matrix materials in the nutraceuticals and pharmaceuticals industries presented a unique opportunity to apply correlation spectroscopy. In a typical formulation the glycerol is reacted with a polyfunctional acid such as citric acid to form the corresponding polyester. The reaction proceeds at atmospheric pressure without added catalyst and at moderately elevated temperature to remove the water of reaction. The extent of reaction is a fundamental parameter related to the performance properties of the polymer as a controlled release material. Properties of particular interest include the delivery rate of material carried by the polymer and the degradation rate of the polymer itself.