Submitted to: Central Hardwoods Forest Conference
Publication Type: Abstract Only
Publication Acceptance Date: 4/15/2008
Publication Date: 4/15/2008
Citation: Lin, C., Gold, M.A., Kremer, R.J., Godsey, L.D. 2008. Screening and Testing Phytochemicals in Eastern Redcedar (Juniperus Virginana) for Development of Potential Entrepreneurial Opportunities [abstract]. Central Hardwoods Forest Conference, April 8-9, 2008, Lafayette, Indiana. General Tech. Dept. NC-188, USDA-Forest Service, St. Paul, Minnesota. 2008 CD-ROM. Interpretive Summary:
Technical Abstract: Eastern redcedar (Juniperus virginiana) is often considered a "trash or nuisance" tree. In some states, this species has been declared invasive and management strategies have been adopted to destroy it. However, value-added phytochemical products from eastern redcedar have the potential to create new industries in regions such as Missouri with an abundant redcedar resource. As a first step toward the development of such industries, it is essential to characterize, and quantify the composition of the individual phytochemicals within various redcedar tissues with modern chromatographic, spectroscopic and bioassay technologies. The analytical steps are followed by an evaluation of potential commercial applications of phytochemical compounds in the agricultural, pharmaceutical, and cosmetic industries. In this study, distilled cedar oil, cedar sawdust, and various tissues including roots, leaves, fruits, branches, sapwoods, and heartwood were collected and intensively extracted with organic solvents. Separation and fractionation of the phytochemicals with a range of polarity were performed by liquid/liquid extraction followed by reverse-phase liquid chromatography. Bioassays were performed to evaluate the potential biological activities (i.e., herbicidal, antifungal, antibacterial, antitermitic, insecticidal, antitumoral) of each fraction. Compounds in the extracts showing high bioactivity in one or more bioassays will be isolated and further purified for chemical characterization and elucidation of molecular structure.