Location: Location not imported yet.Title: Variation in infectivity and adaptation of wild duck- and poultry-origin high pathogenicity and low pathogenicity avian influenza viruses for poultry) Author
Submitted to: American Veterinary Medical Association Abstract
Publication Type: Abstract only
Publication Acceptance Date: 3/31/2008
Publication Date: 7/18/2008
Citation: Swayne, D.E., Slemons, R.D. 2008. Variation in infectivity and adaptation of wild duck- and poultry-origin high pathogenicity and low pathogenicity avian influenza viruses for poultry [abstract]. In: Proceedings of the 145th American Veterinary Medical Association Annual Convention, July 19-22, 2008, New Orleans, Louisiana. 2008 CDROM. Interpretive Summary:
Technical Abstract: Avian influenza (AI) viruses vary in their adaptation which impacts transmission between and infection of different bird species. We determine the intranasal mean bird infectious doses (BID50) for 11 high pathogenicity (HP) AI viruses for layer type chickens (LC), and three low pathogenicity (LP) AI viruses for turkeys (TK), LC, broiler type chickens (BC), ducks (DD), geese (DG) and Japanese quail (JQ). The BID50 for HPAI viruses ranged from 1.2-4.7log10 mean embryo infectious dose (EID50) with a median of 2.9log10. The data suggested a BID50 of <4.7log10 was needed for sustained transmission. For the chicken-origin LPAI virus, the BID50 were <4.7log10 EID50 for JQ, BC and DD, but >5log10 EID50 for TK and LC. With an H4N8 LPAI virus, the BID50 was <4.7log10 for DG, DD, JQ and TK, but for an H5N1 LPAI virus, only DD had BID50 <4.7log10. This suggests that DD are an excellent introductory and maintenance host for LPAI viruses from wild waterfowl which has impact in live poultry markets.