Submitted to: American Veterinary Medical Association Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 7/12/2007
Publication Date: 7/14/2007
Citation: Brown, J.D., Stallknecht, D.E., Swayne, D.E. 2007. Comparative pathology of H5N1 highly pathogenic avian influenza virus infection in avian species in the Orders Anseriformes and Charadriiformes [abstract]. In: Proceedings of the Annual Meeting of the American Association of Avian Pathologists, July 14-18, 2007, Washington, DC. CD-ROM. Interpretive Summary:
Technical Abstract: Thirteen species of ducks, geese, swans and gulls present in the North American wild bird populations were inoculated intranasally with A/Whooper Swan/Mongolia/244/05 (H5N1) avian influenza virus to evaluate the range of viral shedding and pathology within these two avian orders. Based on mortality and the distribution of virus, these species were separated into four categories: 1) 100% mortality with viral antigen disseminated in the vasculature and parenchyma of numerous visceral organs, 2) high mortality with antigen primarily distributed in the brain, pancreas, adrenal glands and heart, 3) moderate mortality with antigen primarily located in the brain, and 4) No mortality and no viral antigen was detected.