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Title: Functional markers of common bean from disease resistance gene othologs

item Miklas, Phillip - Phil

Submitted to: Bean Improvement Cooperative Annual Report
Publication Type: Research Notes
Publication Acceptance Date: 2/1/2007
Publication Date: 5/1/2007
Citation: Talukder, Z.I., Miklas, P.N., Connella, T.P., Hossain, K.G. 2007. Functional markers of common bean from disease resistance gene othologs. Bean Improvement Cooperative Annual Report. 50: 75-76.

Interpretive Summary:

Technical Abstract: Disease infestation is a major constraint for subsistence production and economic yield of common bean. Development of cultivars with improved disease resistance is a primary goal of bean breeding programs throughout the world. Genetic linkage maps have been used to identify DNA markers tightly linked with resistance traits in common bean for purposes of marker-assisted selection. Several types of DNA markers have been used to tag and monitor disease resistance traits but very few of them are functional gene-based markers. Genes conferring resistance to different plant pathogens have been isolated from a variety of species. Comparing the predicted amino acid sequences of cloned resistance (R) genes, researchers were able to identify conserved motifs in R gene products. Compared to major crop species, the limited genomic resources in common bean has created a bottleneck in the development of functional markers. The availability of genomic databases in other important plant and animal species; however, has enabled application of genomic information across species. We have initiated a research project to develop functional molecular markers for localizing disease resistance genes in common bean using the sequence information of conserved NBS-LRR motifs of previously sequenced disease resistance genes in related legumes.