Submitted to: Book Chapter
Publication Type: Book / chapter
Publication Acceptance Date: 10/1/2007
Publication Date: 1/1/2008
Citation: Vermuri, M., Kelley, D.S., Erickson, K. 2008. Health Effects of Foods Rich in Polyphenols. Book Chapter, "Wild-Type Food in Health Promotion and Disease Prevention, The Columbus Concept. De Meester, Fabien; Watson, Ronald R. (Eds.) Humana Press, Chapter 27;pp.393-412. Interpretive Summary:
Technical Abstract: We have reviewed literature regarding the health benefits of foods in phenolic compounds. Numerous epidemiological studies indicate an inverse association between fruit and vegetable intake and the risk of cardiovascular disease, ischemic stroke, and other chronic diseases. Besides providing essential vitamins, minerals, and dietary fiber, fruits contain polyphenols that exhibit antioxidant, anti-inflammatory and lipid lowering properties. Several types of berries, cherries, black grapes, and tea are rich sources of dietary phenolic compounds. There are a number of in vitro studies that demonstrate that these compounds reduce oxidative stress and inflammatory response. Data from human feeding studies are limited and inconsistent. Regardless of the inconsistencies, results from human intervention studies do show reduction in oxidative stress, markers of inflammation, serum triglycerides and LDL-cholesterol wehen the diets were supplemented with fruits or fruit extracts rich in polyphenols. The inconsistencies may be due to the differences in the amount and type of the polyphenols consumed, duration of supplementation, basal diet and health status of the subjects.